Plant Cell Illumina
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (107)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Muramoto, T.
Right arrow Articles by Goodman, H. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Muramoto, T.
Right arrow Articles by Goodman, H. M.
Agricola
Right arrow Articles by Muramoto, T.
Right arrow Articles by Goodman, H. M.
Plant Cell, Vol. 11, 335-348, March 1999, Copyright © 1999, American Society of Plant Physiologists

The Arabidopsis Photomorphogenic Mutant hy1 Is Deficient in Phytochrome Chromophore Biosynthesis as a Result of a Mutation in a Plastid Heme Oxygenase

Takuya Muramotoa, Takayuki Kohchia,b, Akiho Yokotaa, Inhwan Hwangb, and Howard M. Goodmanb
a Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan
b Department of Genetics, Harvard Medical School, and Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114

Correspondence to: Takayuki Kohchi, kouchi{at}bs.aist-nara.ac.jp (E-mail), 81-743-72-5569 (fax)

The HY1 locus of Arabidopsis is necessary for phytochrome chromophore biosynthesis and is defined by mutants that show a long hypocotyl phenotype when grown in the light. We describe here the molecular cloning of the HY1 gene by using chromosome walking and mutant complementation. The product of the HY1 gene shows significant similarity to animal heme oxygenases and contains a possible transit peptide for transport to plastids. Heme oxygenase activity was detected in the HY1 protein expressed in Escherichia coli. Heme oxygenase catalyzes the oxygenation of heme to biliverdin, an activity that is necessary for phytochrome chromophore biosynthesis. The predicted transit peptide is sufficient to transport the green fluorescent protein into chloroplasts. The accumulation of the HY1 protein in plastids was detected by using immunoblot analysis with an anti-HY1 antiserum. These results indicate that the Arabidopsis HY1 gene encodes a plastid heme oxygenase necessary for phytochrome chromophore biosynthesis.




This article has been cited by other articles:


Home page
 Plant Physiol.Home page
S. N. Warnasooriya and B. L. Montgomery
Detection of Spatial-Specific Phytochrome Responses Using Targeted Expression of Biliverdin Reductase in Arabidopsis
Plant Physiology, January 1, 2009; 149(1): 424 - 433.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S.-L. Tu, H.-C. Chen, and L.-W. Ku
Mechanistic Studies of the Phytochromobilin Synthase HY2 from Arabidopsis
J. Biol. Chem., October 10, 2008; 283(41): 27555 - 27564.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
N. Mochizuki, R. Tanaka, A. Tanaka, T. Masuda, and A. Nagatani
The steady-state level of Mg-protoporphyrin IX is not a determinant of plastid-to-nucleus signaling in Arabidopsis
PNAS, September 30, 2008; 105(39): 15184 - 15189.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
K. Guo, K. Xia, and Z.-M. Yang
Regulation of tomato lateral root development by carbon monoxide and involvement in auxin and nitric oxide
J. Exp. Bot., September 1, 2008; 59(12): 3443 - 3452.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
E. Lopez-Juez, E. Dillon, Z. Magyar, S. Khan, S. Hazeldine, S. M. de Jager, J. A.H. Murray, G. T.S. Beemster, L. Bogre, and H. Shanahan
Distinct Light-Initiated Gene Expression and Cell Cycle Programs in the Shoot Apex and Cotyledons of Arabidopsis
PLANT CELL, April 1, 2008; 20(4): 947 - 968.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J.-H. Jung, Y.-H. Seo, P. J. Seo, J. L. Reyes, J. Yun, N.-H. Chua, and C.-M. Park
The GIGANTEA-Regulated MicroRNA172 Mediates Photoperiodic Flowering Independent of CONSTANS in Arabidopsis
PLANT CELL, September 1, 2007; 19(9): 2736 - 2748.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
Q. Zhai, C.-B. Li, W. Zheng, X. Wu, J. Zhao, G. Zhou, H. Jiang, J. Sun, Y. Lou, and C. Li
Phytochrome Chromophore Deficiency Leads to Overproduction of Jasmonic Acid and Elevated Expression of Jasmonate-Responsive Genes in Arabidopsis
Plant Cell Physiol., July 1, 2007; 48(7): 1061 - 1071.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Y.-s. Su and J. C. Lagarias
Light-Independent Phytochrome Signaling Mediated by Dominant GAF Domain Tyrosine Mutants of Arabidopsis Phytochromes in Transgenic Plants
PLANT CELL, July 1, 2007; 19(7): 2124 - 2139.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
S. W. Ryter, J. Alam, and A. M. K. Choi
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
Physiol Rev, April 1, 2006; 86(2): 583 - 650.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
T. J. Emborg, J. M. Walker, B. Noh, and R. D. Vierstra
Multiple Heme Oxygenase Family Members Contribute to the Biosynthesis of the Phytochrome Chromophore in Arabidopsis
Plant Physiology, March 1, 2006; 140(3): 856 - 868.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
Y. Nanasato, K. Akashi, and A. Yokota
Co-expression of Cytochrome b 561 and Ascorbate Oxidase in Leaves of Wild Watermelon under Drought and High Light Conditions
Plant Cell Physiol., September 1, 2005; 46(9): 1515 - 1524.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
T. Muramoto, C. Kami, H. Kataoka, N. Iwata, P. J. Linley, K. Mukougawa, A. Yokota, and T. Kohchi
The Tomato Photomorphogenetic Mutant, aurea, is Deficient in Phytochromobilin Synthase for Phytochrome Chromophore Biosynthesis
Plant Cell Physiol., April 1, 2005; 46(4): 661 - 665.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. Bertrand, M. Benhamed, Y.-F. Li, M. Ayadi, G. Lemonnier, J.-P. Renou, M. Delarue, and D.-X. Zhou
Arabidopsis HAF2 Gene Encoding TATA-binding Protein (TBP)-associated Factor TAF1, Is Required to Integrate Light Signals to Regulate Gene Expression and Growth
J. Biol. Chem., January 14, 2005; 280(2): 1465 - 1473.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. Wegele, R. Tasler, Y. Zeng, M. Rivera, and N. Frankenberg-Dinkel
The Heme Oxygenase(s)-Phytochrome System of Pseudomonas aeruginosa
J. Biol. Chem., October 29, 2004; 279(44): 45791 - 45802.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
R. J.H. Sawers, P. J. Linley, J. F. Gutierrez-Marcos, T. Delli-Bovi, P. R. Farmer, T. Kohchi, M. J. Terry, and T. P. Brutnell
The Elm1 (ZmHy2) Gene of Maize Encodes a Phytochromobilin Synthase
Plant Physiology, September 1, 2004; 136(1): 2771 - 2781.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
K. M. Folta
Green Light Stimulates Early Stem Elongation, Antagonizing Light-Mediated Growth Inhibition
Plant Physiology, July 1, 2004; 135(3): 1407 - 1416.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. Kami, K. Mukougawa, T. Muramoto, A. Yokota, T. Shinomura, J. C. Lagarias, and T. Kohchi
Complementation of phytochrome chromophore-deficient Arabidopsis by expression of phycocyanobilin:ferredoxin oxidoreductase
PNAS, January 27, 2004; 101(4): 1099 - 1104.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
E. Baudouin, P. Frendo, M. Le Gleuher, and A. Puppo
A Medicago sativa haem oxygenase gene is preferentially expressed in root nodules
J. Exp. Bot., January 1, 2004; 55(394): 43 - 47.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. L. DeBlasio, J. L. Mullen, D. R. Luesse, and R. P. Hangarter
Phytochrome Modulation of Blue Light-Induced Chloroplast Movements in Arabidopsis
Plant Physiology, December 1, 2003; 133(4): 1471 - 1479.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Chen, R. Schwab, and J. Chory
Characterization of the requirements for localization of phytochrome B to nuclear bodies
PNAS, November 25, 2003; 100(24): 14493 - 14498.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. M. Alvey, J. A. Karty, E. Roos, J. P. Reilly, and D. M. Kehoe
Lesions in Phycoerythrin Chromophore Biosynthesis in Fremyella diplosiphon Reveal Coordinated Light Regulation of Apoprotein and Pigment Biosynthetic Enzyme Gene Expression
PLANT CELL, October 1, 2003; 15(10): 2448 - 2463.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
T. Muramoto, N. Tsurui, M. J. Terry, A. Yokota, and T. Kohchi
Expression and Biochemical Properties of a Ferredoxin-Dependent Heme Oxygenase Required for Phytochrome Chromophore Synthesis
Plant Physiology, December 1, 2002; 130(4): 1958 - 1966.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
T. Lamparter, N. Michael, F. Mittmann, and B. Esteban
Phytochrome from Agrobacterium tumefaciens has unusual spectral properties and reveals an N-terminal chromophore attachment site
PNAS, September 3, 2002; 99(18): 11628 - 11633.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
R. J.H. Sawers, P. J. Linley, P. R. Farmer, N. P. Hanley, D. E. Costich, M. J. Terry, and T. P. Brutnell
elongated mesocotyl1, a Phytochrome-Deficient Mutant of Maize
Plant Physiology, September 1, 2002; 130(1): 155 - 163.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
M. J. Yanovsky, J. P. Luppi, D. Kirchbauer, O. B. Ogorodnikova, V. A. Sineshchekov, E. Adam, S. Kircher, R. J. Staneloni, E. Schafer, F. Nagy, et al.
Missense Mutation in the PAS2 Domain of Phytochrome A Impairs Subnuclear Localization and a Subset of Responses
PLANT CELL, July 1, 2002; 14(7): 1591 - 1603.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
A. Mouradov, F. Cremer, and G. Coupland
Control of Flowering Time: Interacting Pathways as a Basis for Diversity
PLANT CELL, May 1, 2002; 14(90001): S111 - 130.
[Full Text] [PDF]

Home page
 Plant CellHome page
M. Surpin, R. M. Larkin, and J. Chory
Signal Transduction between the Chloroplast and the Nucleus
PLANT CELL, May 1, 2002; 14(90001): S327 - 338.
[Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Hanzawa, T. Shinomura, K. Inomata, T. Kakiuchi, H. Kinoshita, K. Wada, and M. Furuya
Structural requirement of bilin chromophore for the photosensory specificity of phytochromes A and B
PNAS, April 2, 2002; 99(7): 4725 - 4729.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
R. Meskauskiene, M. Nater, D. Goslings, F. Kessler, R. op den Camp, and K. Apel
FLU: A negative regulator of chlorophyll biosynthesis in Arabidopsisthaliana
PNAS, October 12, 2001; (2001) 221252798.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
G. A. Gambetta and J. C. Lagarias
Genetic engineering of phytochrome biosynthesis in bacteria
PNAS, September 11, 2001; 98(19): 10566 - 10571.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. T. McDowell and J. C. Lagarias
Purification and Biochemical Properties of Phytochromobilin Synthase from Etiolated Oat Seedlings
Plant Physiology, August 1, 2001; 126(4): 1546 - 1554.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. M. Swain, T.-s. Tseng, and N. E. Olszewski
Altered Expression of SPINDLY Affects Gibberellin Response and Plant Development
Plant Physiology, July 1, 2001; 126(3): 1174 - 1185.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
M. J. Prigge and D. R. Wagner
The Arabidopsis SERRATE Gene Encodes a Zinc-Finger Protein Required for Normal Shoot Development
PLANT CELL, June 1, 2001; 13(6): 1263 - 1280.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. Santiago-Ong, R. M. Green, S. Tingay, J. A. Brusslan, and E. M. Tobin
shygrl1 Is a Mutant Affected in Multiple Aspects of Photomorphogenesis
Plant Physiology, June 1, 2001; 126(2): 587 - 600.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. J. Davis, S. H. Bhoo, A. M. Durski, J. M. Walker, and R. D. Vierstra
The Heme-Oxygenase Family Required for Phytochrome Chromophore Biosynthesis Is Necessary for Proper Photomorphogenesis in Higher Plants
Plant Physiology, June 1, 2001; 126(2): 656 - 669.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
N. Frankenberg, K. Mukougawa, T. Kohchi, and J. C. Lagarias
Functional Genomic Analysis of the HY2 Family of Ferredoxin-Dependent Bilin Reductases from Oxygenic Photosynthetic Organisms
PLANT CELL, April 1, 2001; 13(4): 965 - 978.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
N. Mochizuki, J. A. Brusslan, R. Larkin, A. Nagatani, and J. Chory
Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit in plastid-to-nucleus signal transduction
PNAS, February 13, 2001; 98(4): 2053 - 2058.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
N. A. Eckardt
From Darkness into Light: Factors Controlling Photomorphogenesis
PLANT CELL, February 1, 2001; 13(2): 219 - 221.
[Full Text]

Home page
 Plant CellHome page
T. Kohchi, K. Mukougawa, N. Frankenberg, M. Masuda, A. Yokota, and J. C. Lagarias
The Arabidopsis HY2 Gene Encodes Phytochromobilin Synthase, a Ferredoxin-Dependent Biliverdin Reductase
PLANT CELL, February 1, 2001; 13(2): 425 - 436.
[Abstract] [Full Text]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
L. E. Otterbein and A. M. K. Choi
Heme oxygenase: colors of defense against cellular stress
Am J Physiol Lung Cell Mol Physiol, December 1, 2000; 279(6): L1029 - L1037.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
C. Fankhauser and J. Chory
RSF1, an Arabidopsis Locus Implicated in Phytochrome A Signaling
Plant Physiology, September 1, 2000; 124(1): 39 - 46.
[Abstract] [Full Text]

Home page
 Genes Dev.Home page
M. M. Neff, C. Fankhauser, and J. Chory
Light: an indicator of time and place
Genes & Dev., February 1, 2000; 14(3): 257 - 271.
[Full Text]

Home page
 Plant Physiol.Home page
J. Hughes and T. Lamparter
Prokaryotes and Phytochrome. The Connection to Chromophores and Signaling
Plant Physiology, December 1, 1999; 121(4): 1059 - 1068.
[Full Text]

Home page
 Plant Physiol.Home page
B. L. Montgomery, K.-C. Yeh, M. W. Crepeau, and J. C. Lagarias
Modification of Distinct Aspects of Photomorphogenesis via Targeted Expression of Mammalian Biliverdin Reductase in Transgenic Arabidopsis Plants
Plant Physiology, October 1, 1999; 121(2): 629 - 640.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. J. Davis, J. Kurepa, and R. D. Vierstra
The Arabidopsis thaliana HY1 locus, required for phytochrome-chromophore biosynthesis, encodes a protein related to heme oxygenases
PNAS, May 25, 1999; 96(11): 6541 - 6546.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. Fankhauser
The Phytochromes, a Family of Red/Far-red Absorbing Photoreceptors
J. Biol. Chem., April 6, 2001; 276(15): 11453 - 11456.
[Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
R. Meskauskiene, M. Nater, D. Goslings, F. Kessler, R. op den Camp, and K. Apel
FLU: A negative regulator of chlorophyll biosynthesis in Arabidopsisthaliana
PNAS, October 23, 2001; 98(22): 12826 - 12831.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. Martinez-Hernandez, L. Lopez-Ochoa, G. Arguello-Astorga, and L. Herrera-Estrella
Functional Properties and Regulatory Complexity of a Minimal RBCS Light-Responsive Unit Activated by Phytochrome, Cryptochrome, and Plastid Signals
Plant Physiology, April 1, 2002; 128(4): 1223 - 1233.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 1999 by the American Society of Plant Biologists