Plant Cell BIOBASE Corporation
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (43)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Karniol, B.
Right arrow Articles by Chamovitz, D. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Karniol, B.
Right arrow Articles by Chamovitz, D. A.
Agricola
Right arrow Articles by Karniol, B.
Right arrow Articles by Chamovitz, D. A.
Plant Cell, Vol. 11, 839-848, May 1999, Copyright © 1999, American Society of Plant Physiologists

Arabidopsis FUSCA5 Encodes a Novel Phosphoprotein That Is a Component of the COP9 Complex

Baruch Karniola, Przemyslaw Maleca, and Daniel A. Chamovitza
a Department of Plant Sciences, Tel Aviv University, Tel Aviv 69978, Israel

Correspondence to: Daniel A. Chamovitz, chamd{at}post.tau.ac.il (E-mail), 972-3-6409380 (fax)

The COP9 complex is a regulator essential for repression of light-mediated development in Arabidopsis. Using partial amino acid sequence data generated from purified COP9 complexes, we cloned the Arabidopsis cDNA encoding the 27-kD subunit of the COP9 complex and showed that it is encoded by the previously identified FUSCA5 (FUS5) locus. fus5 mutants exhibit constitutive photomorphogenic phenotypes similar to those of cop9 and fus6. Point mutations in FUS5 that led to a loss of FUS5 protein were detected in four fus5 allelic strains. FUS5 contains the PCI/PINT and mitogen-activated protein kinase kinase activation loop motifs and is highly conserved with the mammalian COP9 complex subunit 7 and the Aspergillus nidulans AcoB proteins. FUS5 is present in both complex and monomeric forms. In the COP9 complex, FUS5 may interact directly with FUS6 and COP9. Mutations in FUS6 and COP9 result in a shift in the electrophoretic mobility of FUS5. This shift can be mimicked by in vitro phosphorylation of FUS5 by plant extracts. These findings further support the hypothesis that the COP9 complex is a central and common regulator that may interact with multiple signaling pathways.




This article has been cited by other articles:


Home page
 Plant CellHome page
Y. Zhang, S. Feng, F. Chen, H. Chen, J. Wang, C. McCall, Y. Xiong, and X. W. Deng
Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 Forms a Nuclear E3 Ubiquitin Ligase with DDB1 and CUL4 That Is Involved in Multiple Plant Developmental Processes
PLANT CELL, June 1, 2008; 20(6): 1437 - 1455.
[Abstract] [Full Text] [PDF]

Home page
 GENES CELLSHome page
P. Oren-Giladi, O. Krieger, B. A. Edgar, D. A. Chamovitz, and D. Segal
Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development.
Genes Cells, March 1, 2008; 13(3): 221 - 231.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
G. Gusmaroli, P. Figueroa, G. Serino, and X. W. Deng
Role of the MPN Subunits in COP9 Signalosome Assembly and Activity, and Their Regulatory Interaction with Arabidopsis Cullin3-Based E3 Ligases
PLANT CELL, February 1, 2007; 19(2): 564 - 581.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
Y. Shen, S. Feng, L. Ma, R. Lin, L.-J. Qu, Z. Chen, H. Wang, and X. W. Deng
Arabidopsis FHY1 Protein Stability Is Regulated by Light via Phytochrome A and 26S Proteasome
Plant Physiology, November 1, 2005; 139(3): 1234 - 1243.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
E. M.N. Dohmann, C. Kuhnle, and C. Schwechheimer
Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 Signalosome Subunit 5 Is Sufficient to Cause the cop/det/fus Mutant Phenotype in Arabidopsis
PLANT CELL, July 1, 2005; 17(7): 1967 - 1978.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
G. Gusmaroli, S. Feng, and X. W. Deng
The Arabidopsis CSN5A and CSN5B Subunits Are Present in Distinct COP9 Signalosome Complexes, and Mutations in Their JAMM Domains Exhibit Differential Dominant Negative Effects on Development
PLANT CELL, November 1, 2004; 16(11): 2984 - 3001.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
D. A. Chamovitz and A. Yahalom
A Systems Approach to the COP9 Signalosome
Plant Physiology, June 1, 2003; 132(2): 426 - 427.
[Full Text] [PDF]

Home page
 Plant CellHome page
S. Feng, L. Ma, X. Wang, D. Xie, S. P. Dinesh-Kumar, N. Wei, and X. W. Deng
The COP9 Signalosome Interacts Physically with SCFCOI1 and Modulates Jasmonate Responses
PLANT CELL, May 1, 2003; 15(5): 1083 - 1094.
[Abstract] [Full Text]

Home page
 Plant CellHome page
G. Serino, H. Su, Z. Peng, T. Tsuge, N. Wei, H. Gu, and X. W. Deng
Characterization of the Last Subunit of the Arabidopsis COP9 Signalosome: Implications for the Overall Structure and Origin of the Complex
PLANT CELL, March 1, 2003; 15(3): 719 - 731.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Y. Kagaya, T. Hobo, M. Murata, A. Ban, and T. Hattori
Abscisic Acid-Induced Transcription Is Mediated by Phosphorylation of an Abscisic Acid Response Element Binding Factor, TRAB1
PLANT CELL, December 1, 2002; 14(12): 3177 - 3189.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
E. Oron, M. Mannervik, S. Rencus, O. Harari-Steinberg, S. Neuman-Silberberg, D. Segal, and D. A. Chamovitz
COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster
Development, January 10, 2002; 129(19): 4399 - 4409.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
D. Bech-Otschir, M. Seeger, and W. Dubiel
The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis
J. Cell Sci., January 2, 2002; 115(3): 467 - 473.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
Z. Peng, G. Serino, and X.-W. Deng
A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3
Development, November 1, 2001; 128(21): 4277 - 4288.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Z. Peng, G. Serino, and X.-W. Deng
Molecular Characterization of Subunit 6 of the COP9 Signalosome and Its Role in Multifaceted Developmental Processes in Arabidopsis
PLANT CELL, November 1, 2001; 13(11): 2393 - 2407.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
Z. Peng, J. M. Staub, G. Serino, S. F. Kwok, J. Kurepa, B. D. Bruce, R. D. Vierstra, N. Wei, and X.-W. Deng
The Cellular Level of PR500, a Protein Complex Related to the 19S Regulatory Particle of the Proteasome, Is Regulated in Response to Stresses in Plants
Mol. Biol. Cell, February 1, 2001; 12(2): 383 - 392.
[Abstract] [Full Text]

Home page
 Plant Physiol.Home page
C. S. Hardtke and X.-W. Deng
The Cell Biology of the COP/DET/FUS Proteins. Regulating Proteolysis in Photomorphogenesis and Beyond?
Plant Physiology, December 1, 2000; 124(4): 1548 - 1557.
[Full Text]

Home page
 Plant CellHome page
J. A. Sullivan and J. C. Gray
The Pea light-independent photomorphogenesis1 Mutant Results from Partial Duplication of COP1 Generating an Internal Promoter and Producing Two Distinct Transcripts
PLANT CELL, October 1, 2000; 12(10): 1927 - 1938.
[Abstract] [Full Text]

Home page
 Plant CellHome page
G. Serino, T. Tsuge, S. Kwok, M. Matsui, N. Wei, and X.-W. Deng
Arabidopsis cop8 and fus4 Mutations Define the Same Gene That Encodes Subunit 4 of the COP9 Signalosome
PLANT CELL, October 1, 1999; 11(10): 1967 - 1980.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
A. Yahalom, T.-H. Kim, E. Winter, B. Karniol, A. G. von Arnim, and D. A. Chamovitz
Arabidopsis eIF3e (INT-6) Associates with Both eIF3c and the COP9 Signalosome Subunit CSN7
J. Biol. Chem., January 5, 2001; 276(1): 334 - 340.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
X. Wang, D. Kang, S. Feng, G. Serino, C. Schwechheimer, and N. Wei
CSN1 N-Terminal-dependent Activity Is Required for Arabidopsis Development But Not for Rub1/Nedd8 Deconjugation of Cullins: A Structure-Function Study of CSN1 Subunit of COP9 Signalosome
Mol. Biol. Cell, February 1, 2002; 13(2): 646 - 655.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 1999 by the American Society of Plant Biologists