Plant Cell Huazhong Agricultural University
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (40)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lasswell, J.
Right arrow Articles by Bartel, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lasswell, J.
Right arrow Articles by Bartel, B.
Agricola
Right arrow Articles by Lasswell, J.
Right arrow Articles by Bartel, B.
Plant Cell, Vol. 12, 2395-2408, December 2000, Copyright © 2000, American Society of Plant Physiologists

Cloning and Characterization of IAR1, a Gene Required for Auxin Conjugate Sensitivity in Arabidopsis

Jamie Lasswella, Luise E. Rogga, David C. Nelsona, Catherine Rongeya, and Bonnie Bartela
a Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005-1892

Correspondence to: Bonnie Bartel, bartel{at}rice.edu (E-mail), 713-348-5154 (fax)

Most indole-3-acetic acid (IAA) in higher plants is conjugated to amino acids, sugars, or peptides, and these conjugates are implicated in regulating the concentration of the free hormone. We identified iar1 as an Arabidopsis mutant that is resistant to the inhibitory effects of several IAA–amino acid conjugates but remains sensitive to free IAA. iar1 partially suppresses phenotypes of a mutant that overproduces IAA, suggesting that IAR1 participates in auxin metabolism or response. We used positional information to clone IAR1, which encodes a novel protein with seven predicted transmembrane domains and several His-rich regions. IAR1 has homologs in other multicellular organisms, including Drosophila, nematodes, and mammals; in addition, the mouse homolog KE4 can functionally substitute for IAR1 in vivo. IAR1 also structurally resembles and has detectable sequence similarity to a family of metal transporters. We discuss several possible roles for IAR1 in auxin homeostasis.




This article has been cited by other articles:


Home page
 GeneticsHome page
R. A. Rampey, A. W. Woodward, B. N. Hobbs, M. P. Tierney, B. Lahner, D. E. Salt, and B. Bartel
An Arabidopsis Basic Helix-Loop-Helix Leucine Zipper Protein Modulates Metal Homeostasis and Auxin Conjugate Responsiveness
Genetics, December 1, 2006; 174(4): 1841 - 1857.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Kumanovics, K. E. Poruk, K. A. Osborn, D. M. Ward, and J. Kaplan
YKE4 (YIL023C) Encodes a Bidirectional Zinc Transporter in the Endoplasmic Reticulum of Saccharomyces cerevisiae
J. Biol. Chem., August 11, 2006; 281(32): 22566 - 22574.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
N. Tamura, T. Yoshida, A. Tanaka, R. Sasaki, A. Bando, S. Toh, L. Lepiniec, and N. Kawakami
Isolation and Characterization of High Temperature-Resistant Germination Mutants of Arabidopsis thaliana
Plant Cell Physiol., August 1, 2006; 47(8): 1081 - 1094.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Vanneste, B. De Rybel, G. T.S. Beemster, K. Ljung, I. De Smet, G. Van Isterdael, M. Naudts, R. Iida, W. Gruissem, M. Tasaka, et al.
Cell Cycle Progression in the Pericycle Is Not Sufficient for SOLITARY ROOT/IAA14-Mediated Lateral Root Initiation in Arabidopsis thaliana
PLANT CELL, November 1, 2005; 17(11): 3035 - 3050.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
G. Qin, H. Gu, Y. Zhao, Z. Ma, G. Shi, Y. Yang, E. Pichersky, H. Chen, M. Liu, Z. Chen, et al.
An Indole-3-Acetic Acid Carboxyl Methyltransferase Regulates Arabidopsis Leaf Development
PLANT CELL, October 1, 2005; 17(10): 2693 - 2704.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. Huang, C. P. Kirschke, Y. Zhang, and Y. Y. Yu
The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus
J. Biol. Chem., April 15, 2005; 280(15): 15456 - 15463.
[Abstract] [Full Text] [PDF]

Home page
 ANN BOT (LOND)Home page
A. W. WOODWARD and B. BARTEL
Auxin: Regulation, Action, and Interaction
Ann. Bot., April 1, 2005; 95(5): 707 - 735.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
T. P. Dalton, L. He, B. Wang, M. L. Miller, L. Jin, K. F. Stringer, X. Chang, C. S. Baxter, and D. W. Nebert
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis
PNAS, March 1, 2005; 102(9): 3401 - 3406.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
R. A. Rampey, S. LeClere, M. Kowalczyk, K. Ljung, G. Sandberg, and B. Bartel
A Family of Auxin-Conjugate Hydrolases That Contributes to Free Indole-3-Acetic Acid Levels during Arabidopsis Germination
Plant Physiology, June 1, 2004; 135(2): 978 - 988.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. LeClere, R. A. Rampey, and B. Bartel
IAR4, a Gene Required for Auxin Conjugate Sensitivity in Arabidopsis, Encodes a Pyruvate Dehydrogenase E1{alpha} Homolog
Plant Physiology, June 1, 2004; 135(2): 989 - 999.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Van Doren, W. R. Mathews, M. Samuels, L. A. Moore, H. T. Broihier, and R. Lehmann
fear of intimacy encodes a novel transmembrane protein required for gonad morphogenesis in Drosophila
Development, June 1, 2003; 130(11): 2355 - 2364.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. LeClere, R. Tellez, R. A. Rampey, S. P. T. Matsuda, and B. Bartel
Characterization of a Family of IAA-Amino Acid Conjugate Hydrolases from Arabidopsis
J. Biol. Chem., May 31, 2002; 277(23): 20446 - 20452.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
B. Noh, A. S. Murphy, and E. P. Spalding
Multidrug Resistance-like Genes of Arabidopsis Required for Auxin Transport and Auxin-Mediated Development
PLANT CELL, November 1, 2001; 13(11): 2441 - 2454.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
L. E. Rogg, J. Lasswell, and B. Bartel
A Gain-of-Function Mutation in IAA28 Suppresses Lateral Root Development
PLANT CELL, March 1, 2001; 13(3): 465 - 480.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2000 by the American Society of Plant Biologists