Plant Cell Illumina
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (44)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yalovsky, S.
Right arrow Articles by Gruissem, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yalovsky, S.
Right arrow Articles by Gruissem, W.
Agricola
Right arrow Articles by Yalovsky, S.
Right arrow Articles by Gruissem, W.
Plant Cell, Vol. 12, 1257-1266, August 2000, Copyright © 2000, American Society of Plant Physiologists

Prenylation of the Floral Transcription Factor APETALA1 Modulates Its Function

Shaul Yalovskya, Manuel Rodríguez-Concepcióna, Keren Brachaa, Gabriela Toledo-Ortiza, and Wilhelm Gruissema
a Department of Plant and Microbial Biology, University of California, Berkeley, California 94720-3102

Correspondence to: Wilhelm Gruissem, Current address: Institute of Plant Sciences, Swiss Federal Institute of Technology, ETH Zentrum, LFW E57.1, CH-8092 Zurich, Switzerland., wilhelm.gruissem{at}ipw.biol.ethz.ch (E-mail), 41-1-632-10-79 (fax)

The Arabidopsis MADS box transcription factor APETALA1 (AP1) was identified as a substrate for farnesyltransferase and shown to be farnesylated efficiently both in vitro and in vivo. AP1 regulates the transition from inflorescence shoot to floral meristems and the development of sepals and petals. AP1 fused to green fluorescent protein (GFP) retained transcription factor activity and directed the expected terminal flower phenotype when ectopically expressed in transgenic Arabidopsis. However, ap1mS, a farnesyl cysteine–acceptor mutant of AP1, as well as the GFP–ap1mS fusion protein failed to direct the development of compound terminal flowers but instead induced novel phenotypes when ectopically expressed in Arabidopsis. Similarly, compound terminal flowers did not develop in era1-2 transformants that ectopically expressed AP1. Together, the results demonstrate that AP1 is a target of farnesyltransferase and suggest that farnesylation alters the function and perhaps specificity of the transcription factor.




This article has been cited by other articles:


Home page
 Plant Physiol.Home page
A. Galichet, K. Hoyerova, M. Kaminek, and W. Gruissem
Farnesylation Directs AtIPT3 Subcellular Localization and Modulates Cytokinin Biosynthesis in Arabidopsis
Plant Physiology, March 1, 2008; 146(3): 1155 - 1164.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Z. Kevei, G. Lougnon, P. Mergaert, G. V. Horvath, A. Kereszt, D. Jayaraman, N. Zaman, F. Marcel, K. Regulski, G. B. Kiss, et al.
3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase1 Interacts with NORK and Is Crucial for Nodulation in Medicago truncatula
PLANT CELL, December 1, 2007; 19(12): 3974 - 3989.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
C. Liu, J. Zhou, K. Bracha-Drori, S. Yalovsky, T. Ito, and H. Yu
Specification of Arabidopsis floral meristem identity by repression of flowering time genes
Development, May 15, 2007; 134(10): 1901 - 1910.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
Q. Zeng, X. Wang, and M. P. Running
Dual Lipid Modification of Arabidopsis G{gamma}-Subunits Is Required for Efficient Plasma Membrane Targeting
Plant Physiology, March 1, 2007; 143(3): 1119 - 1131.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. Galichet and W. Gruissem
Developmentally Controlled Farnesylation Modulates AtNAP1;1 Function in Cell Proliferation and Cell Expansion during Arabidopsis Leaf Development
Plant Physiology, December 1, 2006; 142(4): 1412 - 1426.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
L. C. Hileman, J. F. Sundstrom, A. Litt, M. Chen, T. Shumba, and V. F. Irish
Molecular and Phylogenetic Analyses of the MADS-Box Gene Family in Tomato
Mol. Biol. Evol., November 1, 2006; 23(11): 2245 - 2258.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
R. Benlloch, I. d'Erfurth, C. Ferrandiz, V. Cosson, J. P. Beltran, L. A. Canas, A. Kondorosi, F. Madueno, and P. Ratet
Isolation of mtpim Proves Tnt1 a Useful Reverse Genetics Tool in Medicago truncatula and Uncovers New Aspects of AP1-Like Functions in Legumes
Plant Physiology, November 1, 2006; 142(3): 972 - 983.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
B. P. Downes, S. A. Saracco, S. S. Lee, D. N. Crowell, and R. D. Vierstra
MUBs, a Family of Ubiquitin-fold Proteins That Are Plasma Membrane-anchored by Prenylation
J. Biol. Chem., September 15, 2006; 281(37): 27145 - 27157.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
C. P. Scutt, M. Vinauger-Douard, C. Fourquin, C. Finet, and C. Dumas
An evolutionary perspective on the regulation of carpel development
J. Exp. Bot., July 1, 2006; 57(10): 2143 - 2152.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. Berbel, C. Navarro, C. Ferrandiz, L. A. Canas, J.-P. Beltran, and F. Madueno
Functional Conservation of PISTILLATA Activity in a Pea Homolog Lacking the PI Motif
Plant Physiology, September 1, 2005; 139(1): 174 - 185.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
V. Hecht, F. Foucher, C. Ferrandiz, R. Macknight, C. Navarro, J. Morin, M. E. Vardy, N. Ellis, J. P. Beltran, C. Rameau, et al.
Conservation of Arabidopsis Flowering Genes in Model Legumes
Plant Physiology, April 1, 2005; 137(4): 1420 - 1434.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
F. Fornara, L. Parenicova, G. Falasca, N. Pelucchi, S. Masiero, S. Ciannamea, Z. Lopez-Dee, M. M. Altamura, L. Colombo, and M. M. Kater
Functional Characterization of OsMADS18, a Member of the AP1/SQUA Subfamily of MADS Box Genes
Plant Physiology, August 1, 2004; 135(4): 2207 - 2219.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. P. Running, M. Lavy, H. Sternberg, A. Galichet, W. Gruissem, S. Hake, N. Ori, and S. Yalovsky
Enlarged meristems and delayed growth in plp mutants result from lack of CaaX prenyltransferases
PNAS, May 18, 2004; 101(20): 7815 - 7820.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. Litt and V. F. Irish
Duplication and Diversification in the APETALA1/FRUITFULL Floral Homeotic Gene Lineage: Implications for the Evolution of Floral Development
Genetics, October 1, 2003; 165(2): 821 - 833.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
J. Danyluk, N. A. Kane, G. Breton, A. E. Limin, D. B. Fowler, and F. Sarhan
TaVRT-1, a Putative Transcription Factor Associated with Vegetative to Reproductive Transition in Cereals
Plant Physiology, August 1, 2003; 132(4): 1849 - 1860.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
V. Hugouvieux, Y. Murata, J. J. Young, J. M. Kwak, D. Z. Mackesy, and J. I. Schroeder
Localization, Ion Channel Regulation, and Genetic Interactions during Abscisic Acid Signaling of the Nuclear mRNA Cap-Binding Protein, ABH1
Plant Physiology, November 1, 2002; 130(3): 1276 - 1287.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
G. J. Allen, Y. Murata, S. P. Chu, M. Nafisi, and J. I. Schroeder
Hypersensitivity of Abscisic Acid-Induced Cytosolic Calcium Increases in the Arabidopsis Farnesyltransferase Mutant era1-2
PLANT CELL, July 1, 2002; 14(7): 1649 - 1662.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
S. Jang, K. An, S. Lee, and G. An
Characterization of Tobacco MADS-box Genes Involved in Floral Initiation
Plant Cell Physiol., February 1, 2002; 43(2): 230 - 238.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
D. Caldelari, H. Sternberg, M. Rodriguez-Concepcion, W. Gruissem, and S. Yalovsky
Efficient Prenylation by a Plant Geranylgeranyltransferase-I Requires a Functional CaaL Box Motif and a Proximal Polybasic Domain
Plant Physiology, August 1, 2001; 126(4): 1416 - 1429.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Yalovsky, A. Kulukian, M. Rodríguez-Concepción, C. A. Young, and W. Gruissem
Functional Requirement of Plant Farnesyltransferase during Development in Arabidopsis
PLANT CELL, August 1, 2000; 12(8): 1267 - 1278.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2000 by the American Society of Plant Biologists