Plant Cell EPICENTRE Biotechnologies
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (88)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Spelt, C.
Right arrow Articles by Koes, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Spelt, C.
Right arrow Articles by Koes, R.
Agricola
Right arrow Articles by Spelt, C.
Right arrow Articles by Koes, R.
Plant Cell, Vol. 12, 1619-1632, September 2000, Copyright © 2000, American Society of Plant Physiologists

anthocyanin1 of Petunia Encodes a Basic Helix-Loop-Helix Protein That Directly Activates Transcription of Structural Anthocyanin Genes

Cornelis Spelta, Francesca Quattrocchioa, Joseph N. M. Mola, and Ronald Koesa
a Department of Genetics, Institute for Molecular Biological Sciences, Vrije Universiteit, Biocentrum Amsterdam, de Boelelaan 1087, 1081 HV Amsterdam, The Netherlands

Correspondence to: Ronald Koes, koes{at}bio.vu.nl (E-mail), 31-20-4447155 (fax)

The petunia loci anthocyanin1 (an1), an2, an4, and an11 are required for the transcription of anthocyanin biosynthetic genes in floral organs. The an2 and an11 loci were recently cloned and shown to encode a MYB-domain transcriptional activator and a cytosolic WD40 protein, respectively. Here, we report the isolation of an1 by transposon tagging. an1 encodes a new member of the basic helix-loop-helix family of transcription factors that is functionally and evolutionarily distinct from JAF13, the apparent petunia ortholog of maize RED1 and snapdragon DELILA. We provide genetic evidence that the transcription factors encoded by an1, an2, and an4 operate in an unexpectedly complex regulatory hierarchy. In leaves, ectopic expression of AN2 induces an1 expression, whereas in anthers, an1 expression depends on an4, encoding (or controlling) a MYB protein that is paralogous to AN2. Experiments with transgenic plants expressing a post-translationally controlled AN1–GLUCOCORTICOID RECEPTOR fusion protein indicated that independent of protein synthesis, AN1 directly activates the expression of the dfrA gene encoding the enzyme dihydroflavonol 4-reductase and of Pmyb27 encoding a MYB-domain protein of unknown function.




This article has been cited by other articles:


Home page
 Plant Cell PhysiolHome page
T. Nakatsuka, K. S. Haruta, C. Pitaksutheepong, Y. Abe, Y. Kakizaki, K. Yamamoto, N. Shimada, S. Yamamura, and M. Nishihara
Identification and Characterization of R2R3-MYB and bHLH Transcription Factors Regulating Anthocyanin Biosynthesis in Gentian Flowers
Plant Cell Physiol., December 1, 2008; 49(12): 1818 - 1829.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
L. Deluc, J. Bogs, A. R. Walker, T. Ferrier, A. Decendit, J.-M. Merillon, S. P. Robinson, and F. Barrieu
The Transcription Factor VvMYB5b Contributes to the Regulation of Anthocyanin and Proanthocyanidin Biosynthesis in Developing Grape Berries
Plant Physiology, August 1, 2008; 147(4): 2041 - 2053.
[Abstract] [Full Text] [PDF]

Home page
 jashsHome page
H. Ma, M. Pooler, and R. Griesbach
Ratio of Myc and Myb Transcription Factors Regulates Anthocyanin Production in Orchid Flowers
J. Amer. Soc. Hort. Sci., January 1, 2008; 133(1): 133 - 138.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
M. A. Streisfeld and M. D. Rausher
Relaxed Constraint and Evolutionary Rate Variation between Basic Helix-Loop-Helix Floral Anthocyanin Regulators in Ipomoea
Mol. Biol. Evol., December 1, 2007; 24(12): 2816 - 2826.
[Abstract] [Full Text] [PDF]

Home page
 jashsHome page
R. J. Griesbach, R. M. Beck, J. Hammond, and J. R. Stommel
Gene Expression in the Star Mutation of Petunia xhybrida Vilm
J. Amer. Soc. Hort. Sci., September 1, 2007; 132(5): 680 - 690.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Agarwal, Y. Hao, A. Kapoor, C.-H. Dong, H. Fujii, X. Zheng, and J.-K. Zhu
A R2R3 Type MYB Transcription Factor Is Involved in the Cold Regulation of CBF Genes and in Acquired Freezing Tolerance
J. Biol. Chem., December 8, 2006; 281(49): 37636 - 37645.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
N. Li, D.-S. Zhang, H.-S. Liu, C.-S. Yin, X.-x. Li, W.-q. Liang, Z. Yuan, B. Xu, H.-W. Chu, J. Wang, et al.
The Rice Tapetum Degeneration Retardation Gene Is Required for Tapetum Degradation and Anther Development
PLANT CELL, November 1, 2006; 18(11): 2999 - 3014.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
F. Quattrocchio, W. Verweij, A. Kroon, C. Spelt, J. Mol, and R. Koes
PH4 of Petunia Is an R2R3 MYB Protein That Activates Vacuolar Acidification through Interactions with Basic-Helix-Loop-Helix Transcription Factors of the Anthocyanin Pathway
PLANT CELL, May 1, 2006; 18(5): 1274 - 1291.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
Y. Morita, M. Saitoh, A. Hoshino, E. Nitasaka, and S. Iida
Isolation of cDNAs for R2R3-MYB, bHLH and WDR Transcriptional Regulators and Identification of c and ca Mutations Conferring White Flowers in the Japanese Morning Glory
Plant Cell Physiol., April 1, 2006; 47(4): 457 - 470.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
K. Schwinn, J. Venail, Y. Shang, S. Mackay, V. Alm, E. Butelli, R. Oyama, P. Bailey, K. Davies, and C. Martin
A Small Family of MYB-Regulatory Genes Controls Floral Pigmentation Intensity and Patterning in the Genus Antirrhinum
PLANT CELL, April 1, 2006; 18(4): 831 - 851.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
M. T. Sweeney, M. J. Thomson, B. E. Pfeil, and S. McCouch
Caught Red-Handed: Rc Encodes a Basic Helix-Loop-Helix Protein Conditioning Red Pericarp in Rice
PLANT CELL, February 1, 2006; 18(2): 283 - 294.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J. C. Verdonk, M. A. Haring, A. J. van Tunen, and R. C. Schuurink
ODORANT1 Regulates Fragrance Biosynthesis in Petunia Flowers
PLANT CELL, May 1, 2005; 17(5): 1612 - 1624.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
K. Ament, M. R. Kant, M. W. Sabelis, M. A. Haring, and R. C. Schuurink
Jasmonic Acid Is a Key Regulator of Spider Mite-Induced Volatile Terpenoid and Methyl Salicylate Emission in Tomato
Plant Physiology, August 1, 2004; 135(4): 2025 - 2037.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. Matsushima, Y. Fukao, M. Nishimura, and I. Hara-Nishimura
NAI1 Gene Encodes a Basic-Helix-Loop-Helix-Type Putative Transcription Factor That Regulates the Formation of an Endoplasmic Reticulum-Derived Structure, the ER Body
PLANT CELL, June 1, 2004; 16(6): 1536 - 1549.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. R. Kant, K. Ament, M. W. Sabelis, M. A. Haring, and R. C. Schuurink
Differential Timing of Spider Mite-Induced Direct and Indirect Defenses in Tomato Plants
Plant Physiology, May 1, 2004; 135(1): 483 - 495.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
C. C. Carey, J. T. Strahle, D. A. Selinger, and V. L. Chandler
Mutations in the pale aleurone color1 Regulatory Gene of the Zea mays Anthocyanin Pathway Have Distinct Phenotypes Relative to the Functionally Similar TRANSPARENT TESTA GLABRA1 Gene in Arabidopsis thaliana
PLANT CELL, February 1, 2004; 16(2): 450 - 464.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
P. Elomaa, A. Uimari, M. Mehto, V. A. Albert, R. A.E. Laitinen, and T. H. Teeri
Activation of Anthocyanin Biosynthesis in Gerbera hybrida (Asteraceae) Suggests Conserved Protein-Protein and Protein-Promoter Interactions between the Anciently Diverged Monocots and Eudicots
Plant Physiology, December 1, 2003; 133(4): 1831 - 1842.
[Abstract] [Full Text]

Home page
 Mol Biol EvolHome page
M. A. Heim, M. Jakoby, M. Werber, C. Martin, B. Weisshaar, and P. C. Bailey
The Basic Helix-Loop-Helix Transcription Factor Family in Plants: A Genome-Wide Study of Protein Structure and Functional Diversity
Mol. Biol. Evol., May 1, 2003; 20(5): 735 - 747.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
V. Chinnusamy, M. Ohta, S. Kanrar, B.-h. Lee, X. Hong, M. Agarwal, and J.-K. Zhu
ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis
Genes & Dev., April 15, 2003; 17(8): 1043 - 1054.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
N. Nesi, I. Debeaujon, C. Jond, A. J. Stewart, G. I. Jenkins, M. Caboche, and L. Lepiniec
The TRANSPARENT TESTA16 Locus Encodes the ARABIDOPSIS BSISTER MADS Domain Protein and Is Required for Proper Development and Pigmentation of the Seed Coat
PLANT CELL, October 1, 2002; 14(10): 2463 - 2479.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
C. Spelt, F. Quattrocchio, J. Mol, and R. Koes
ANTHOCYANIN1 of Petunia Controls Pigment Synthesis, Vacuolar pH, and Seed Coat Development by Genetically Distinct Mechanisms
PLANT CELL, September 1, 2002; 14(9): 2121 - 2135.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
G. A. Smolen, L. Pawlowski, S. E. Wilensky, and J. Bender
Dominant Alleles of the Basic Helix-Loop-Helix Transcription Factor ATR2 Activate Stress-Responsive Genes in Arabidopsis
Genetics, July 1, 2002; 161(3): 1235 - 1246.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
Y. Itoh, D. Higeta, A. Suzuki, H. Yoshida, and Y. Ozeki
Excision of Transposable Elements from the Chalcone Isomerase and Dihydroflavonol 4-Reductase Genes May Contribute to the Variegation of the Yellow-Flowered Carnation (Dianthus caryophyllus)
Plant Cell Physiol., May 15, 2002; 43(5): 578 - 585.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
R. Tobena-Santamaria, M. Bliek, K. Ljung, G. Sandberg, J. N.M. Mol, E. Souer, and R. Koes
FLOOZY of petunia is a flavin mono-oxygenase-like protein required for the specification of leaf and flower architecture
Genes & Dev., March 15, 2002; 16(6): 753 - 763.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
B. Winkel-Shirley
It Takes a Garden. How Work on Diverse Plant Species Has Contributed to an Understanding of Flavonoid Metabolism
Plant Physiology, December 1, 2001; 127(4): 1399 - 1404.
[Full Text] [PDF]

Home page
 Plant CellHome page
N. Nesi, C. Jond, I. Debeaujon, M. Caboche, and L. Lepiniec
The Arabidopsis TT2 Gene Encodes an R2R3 MYB Domain Protein That Acts as a Key Determinant for Proanthocyanidin Accumulation in Developing Seed
PLANT CELL, September 1, 2001; 13(9): 2099 - 2114.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
B. Winkel-Shirley
Flavonoid Biosynthesis. A Colorful Model for Genetics, Biochemistry, Cell Biology, and Biotechnology
Plant Physiology, June 1, 2001; 126(2): 485 - 493.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2000 by the American Society of Plant Biologists