Plant Cell Illumina
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

First published online November 26, 2002; 10.1105/tpc.006338

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
14/12/3213    most recent
tpc.006338v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (24)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ramakrishna, W.
Right arrow Articles by Bennetzen, J. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ramakrishna, W.
Right arrow Articles by Bennetzen, J. L.
Agricola
Right arrow Articles by Ramakrishna, W.
Right arrow Articles by Bennetzen, J. L.
The Plant Cell, Vol. 14, 3213-3223, December 2002, Copyright © 2002,
American Society of Plant Biologists

Structural Analysis of the Maize Rp1 Complex Reveals Numerous Sites and Unexpected Mechanisms of Local Rearrangement

Wusirika Ramakrishnaa, John Embertona, Matthew Ogdena, Phillip SanMiguelb and Jeffrey L. Bennetzen1,a

a Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907
b Purdue University Genomics Core, Purdue University, West Lafayette, Indiana 47907

1 To whom correspondence should be addressed. E-mail maize{at}bilbo.bio.purdue.edu; fax 765-496-1496

Rp1 is a complex disease resistance locus in maize that is exceptional in both allelic variability and meiotic instability. Genomic sequence analysis of three maize BACs from the Rp1 region of the B73 inbred line revealed 4 Rp1 homologs and 18 other gene-homologous sequences, of which at least 16 are truncated. Thirteen of the truncated genes are found in three clusters, suggesting that they arose from multiple illegitimate break repairs at the same sites or from complex repairs of each of these sites with multiple unlinked DNA templates. A 43-kb region that contains an Rp1 homolog, six truncated genes, and three Opie retrotransposons was found to be duplicated in this region. This duplication is relatively recent, occurring after the insertion of the three Opie elements. The breakpoints of the duplication are outside of any genes or identified repeat sequence, suggesting a duplication mechanism that did not involve unequal recombination. A physical map and partial sequencing of the Rp1 complex indicate the presence of 15 Rp1 homologs in regions of ~250 and 300 kb in the B73 inbred line. Comparison of fully sequenced Rp1-homologous sequences in the region demonstrates a history of unequal recombination and diversifying selection within the Leu-rich repeat 2 region, resulting in chimeric gene structures.




This article has been cited by other articles:


Home page
 GeneticsHome page
H. Yi and E. J. Richards
Gene Duplication and Hypermutation of the Pathogen Resistance Gene SNC1 in the Arabidopsis bal Variant
Genetics, December 1, 2009; 183(4): 1227 - 1234.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. Ducrocq, C. Giauffret, D. Madur, V. Combes, F. Dumas, S. Jouanne, D. Coubriche, P. Jamin, L. Moreau, and A. Charcosset
Fine Mapping and Haplotype Structure Analysis of a Major Flowering Time Quantitative Trait Locus on Maize Chromosome 10
Genetics, December 1, 2009; 183(4): 1555 - 1563.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J. S.S. Ammiraju, F. Lu, A. Sanyal, Y. Yu, X. Song, N. Jiang, A. C. Pontaroli, T. Rambo, J. Currie, K. Collura, et al.
Dynamic Evolution of Oryza Genomes Is Revealed by Comparative Genomic Analysis of a Genus-Wide Vertical Data Set
PLANT CELL, December 1, 2008; 20(12): 3191 - 3209.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
R. Liu, C. Vitte, J. Ma, A. A. Mahama, T. Dhliwayo, M. Lee, and J. L. Bennetzen
A GeneTrek analysis of the maize genome
PNAS, July 10, 2007; 104(28): 11844 - 11849.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. D. Yandeau-Nelson, Y. Xia, J. Li, M. G. Neuffer, and P. S. Schnable
Unequal Sister Chromatid and Homolog Recombination at a Tandem Duplication of the a1 Locus in Maize
Genetics, August 1, 2006; 173(4): 2211 - 2226.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
G. He, X. Luo, F. Tian, K. Li, Z. Zhu, W. Su, X. Qian, Y. Fu, X. Wang, C. Sun, et al.
Haplotype variation in structure and expression of a gene cluster associated with a quantitative trait locus for improved yield in rice
Genome Res., May 1, 2006; 16(5): 618 - 626.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. Lai, Y. Li, J. Messing, and H. K. Dooner
From the Cover: Gene movement by Helitron transposons contributes to the haplotype variability of maize
PNAS, June 21, 2005; 102(25): 9068 - 9073.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
N. Chantret, J. Salse, F. Sabot, S. Rahman, A. Bellec, B. Laubin, I. Dubois, C. Dossat, P. Sourdille, P. Joudrier, et al.
Molecular Basis of Evolutionary Events That Shaped the Hardness Locus in Diploid and Polyploid Wheat Species (Triticum and Aegilops)
PLANT CELL, April 1, 2005; 17(4): 1033 - 1045.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Brunner, K. Fengler, M. Morgante, S. Tingey, and A. Rafalski
Evolution of DNA Sequence Nonhomologies among Maize Inbreds
PLANT CELL, February 1, 2005; 17(2): 343 - 360.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S.-F. Peng, Y.-P. Lin, and B.-y. Lin
Characterization of AFLP Sequences From Regions of Maize B Chromosome Defined by 12 B-10L Translocations
Genetics, January 1, 2005; 169(1): 375 - 388.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. N. Topp, C. X. Zhong, and R. K. Dawe
Centromere-encoded RNAs are integral components of the maize kinetochore
PNAS, November 9, 2004; 101(45): 15986 - 15991.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
H. Kuang, S.-S. Woo, B. C. Meyers, E. Nevo, and R. W. Michelmore
Multiple Genetic Processes Result in Heterogeneous Rates of Evolution within the Major Cluster Disease Resistance Genes in Lettuce
PLANT CELL, November 1, 2004; 16(11): 2870 - 2894.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
J. Lai, J. Ma, Z. Swigonova, W. Ramakrishna, E. Linton, V. Llaca, B. Tanyolac, Y.-J. Park, O-Y. Jeong, J. L. Bennetzen, et al.
Gene Loss and Movement in the Maize Genome
Genome Res., October 1, 2004; 14(10a): 1924 - 1931.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. M. Smith, A. J. Pryor, and S. H. Hulbert
Allelic and Haplotypic Diversity at the Rp1 Rust Resistance Locus of Maize
Genetics, August 1, 2004; 167(4): 1939 - 1947.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
C. E. Grover, H. Kim, R. A. Wing, A. H. Paterson, and J. F. Wendel
Incongruent Patterns of Local and Global Genome Size Evolution in Cotton
Genome Res., August 1, 2004; 14(8): 1474 - 1482.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
R. M. Clark, E. Linton, J. Messing, and J. F. Doebley
Inaugural Article: Pattern of diversity in the genomic region near the maize domestication gene tb1
PNAS, January 20, 2004; 101(3): 700 - 707.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
T. Wicker, N. Yahiaoui, R. Guyot, E. Schlagenhauf, Z.-D. Liu, J. Dubcovsky, and B. Keller
Rapid Genome Divergence at Orthologous Low Molecular Weight Glutenin Loci of the A and Am Genomes of Wheat
PLANT CELL, May 1, 2003; 15(5): 1186 - 1197.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2002 by the American Society of Plant Biologists