Plant Cell Hybrigenics The Protein Interactions Experts
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (49)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cardinale, F.
Right arrow Articles by Hirt, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cardinale, F.
Right arrow Articles by Hirt, H.
Agricola
Right arrow Articles by Cardinale, F.
Right arrow Articles by Hirt, H.
The Plant Cell, Vol. 14, 703-711, March 2002, Copyright © 2002,
American Society of Plant Biologists

Convergence and Divergence of Stress-Induced Mitogen-Activated Protein Kinase Signaling Pathways at the Level of Two Distinct Mitogen-Activated Protein Kinase Kinases

Francesca Cardinale1, Irute Meskiene, Fatma Ouaked and Heribert Hirt2

Institute of Microbiology and Genetics, Vienna Biocenter, University of Vienna, Dr. Bohrgasse 9, A-1030 Vienna, Austria

2 To whom correspondence should be addressed. E-mail hehi{at}gem.univie.ac.at; fax 43-1-42779546

Plants respond to biotic and abiotic stresses by inducing overlapping sets of mitogen-activated protein kinases (MAPKs) and response genes. To define the mechanisms of how different signals can activate a common signaling pathway, upstream activators of SIMK, a salt stress– and pathogen-induced alfalfa MAPK, were identified. Here, we compare the properties of SIMKK, a MAPK kinase (MAPKK) that mediates the activation of SIMK by salt stress, with those of PRKK, a distantly related novel MAPKK. Although both SIMKK and PRKK show strongest interaction with SIMK, SIMKK can activate SIMK without stimulation by upstream factors. In contrast, PRKK requires activation by an upstream activated MAPKK kinase. SIMKK mediates pathogen elicitor signaling and salt stress, but PRKK transmits only elicitor-induced MAPK activation. Of four tested MAPKs, PRKK activates three of them (SIMK, MMK3, and SAMK) upon elicitor treatment of cells. However, PRKK is unable to activate any MAPK upon salt stress. In contrast, SIMKK activates SIMK and MMK3 in response to elicitor, but it activates only SIMK upon salt stress. These data show that (1) MAPKKs function as convergence points for stress signals, (2) MAPKKs activate multiple MAPKs, and (3) signaling specificity is obtained not only through the inherent affinities of MAPKK-MAPK combinations but also through stress signal–dependent intracellular mechanisms.




This article has been cited by other articles:


Home page
 Plant Physiol.Home page
C. Zhou, Z. Cai, Y. Guo, and S. Gan
An Arabidopsis Mitogen-Activated Protein Kinase Cascade, MKK9-MPK6, Plays a Role in Leaf Senescence
Plant Physiology, May 1, 2009; 150(1): 167 - 177.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
S. C. Popescu, G. V. Popescu, S. Bachan, Z. Zhang, M. Gerstein, M. Snyder, and S. P. Dinesh-Kumar
MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays
Genes & Dev., January 1, 2009; 23(1): 80 - 92.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. Xu, Y. Li, Y. Wang, H. Liu, L. Lei, H. Yang, G. Liu, and D. Ren
Activation of MAPK Kinase 9 Induces Ethylene and Camalexin Biosynthesis and Enhances Sensitivity to Salt Stress in Arabidopsis
J. Biol. Chem., October 3, 2008; 283(40): 26996 - 27006.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. AbuQamar, M.-F. Chai, H. Luo, F. Song, and T. Mengiste
Tomato Protein Kinase 1b Mediates Signaling of Plant Responses to Necrotrophic Fungi and Insect Herbivory
PLANT CELL, July 1, 2008; 20(7): 1964 - 1983.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Virol.Home page
M. Babu, A. G. Gagarinova, J. E. Brandle, and A. Wang
Association of the transcriptional response of soybean plants with soybean mosaic virus systemic infection
J. Gen. Virol., April 1, 2008; 89(4): 1069 - 1080.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. Doczi, G. Brader, A. Pettko-Szandtner, I. Rajh, A. Djamei, A. Pitzschke, M. Teige, and H. Hirt
The Arabidopsis Mitogen-Activated Protein Kinase Kinase MKK3 Is Upstream of Group C Mitogen-Activated Protein Kinases and Participates in Pathogen Signaling
PLANT CELL, October 1, 2007; 19(10): 3266 - 3279.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
M. Fernandez-Pascual, M. M. Lucas, M. R. de Felipe, L. Bosca, H. Hirt, and M. P. Golvano
Involvement of mitogen-activated protein kinases in the symbiosis Bradyrhizobium-Lupinus
J. Exp. Bot., August 1, 2006; 57(11): 2735 - 2742.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Y. Dai, H. Wang, B. Li, J. Huang, X. Liu, Y. Zhou, Z. Mou, and J. Li
Increased Expression of MAP KINASE KINASE7 Causes Deficiency in Polar Auxin Transport and Leads to Plant Architectural Abnormality in Arabidopsis
PLANT CELL, February 1, 2006; 18(2): 308 - 320.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
P. Veronese, H. Nakagami, B. Bluhm, S. AbuQamar, X. Chen, J. Salmeron, R. A. Dietrich, H. Hirt, and T. Mengiste
The Membrane-Anchored BOTRYTIS-INDUCED KINASE1 Plays Distinct Roles in Arabidopsis Resistance to Necrotrophic and Biotrophic Pathogens
PLANT CELL, January 1, 2006; 18(1): 257 - 273.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. Boudsocq and C. Lauriere
Osmotic Signaling in Plants. Multiple Pathways Mediated by Emerging Kinase Families
Plant Physiology, July 1, 2005; 138(3): 1185 - 1194.
[Full Text] [PDF]

Home page
 Plant Physiol.Home page
C. Jonak, H. Nakagami, and H. Hirt
Heavy Metal Stress. Activation of Distinct Mitogen-Activated Protein Kinase Pathways by Copper and Cadmium
Plant Physiology, October 1, 2004; 136(2): 3276 - 3283.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. Nakagami, S. Kiegerl, and H. Hirt
OMTK1, a Novel MAPKKK, Channels Oxidative Stress Signaling through Direct MAPK Interaction
J. Biol. Chem., June 25, 2004; 279(26): 26959 - 26966.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. Lee, J. J. Rudd, V. K. Macioszek, and D. Scheel
Dynamic Changes in the Localization of MAPK Cascade Components Controlling Pathogenesis-related (PR) Gene Expression during Innate Immunity in Parsley
J. Biol. Chem., May 21, 2004; 279(21): 22440 - 22448.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Mayrose, A. Bonshtien, and G. Sessa
LeMPK3 Is a Mitogen-activated Protein Kinase with Dual Specificity Induced during Tomato Defense and Wounding Responses
J. Biol. Chem., April 9, 2004; 279(15): 14819 - 14827.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
V. Chinnusamy, K. Schumaker, and J.-K. Zhu
Molecular genetic perspectives on cross-talk and specificity in abiotic stress signalling in plants
J. Exp. Bot., January 2, 2004; 55(395): 225 - 236.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. R. Holley, R. D. Yalamanchili, D. S. Moura, C. A. Ryan, and J. W. Stratmann
Convergence of Signaling Pathways Induced by Systemin, Oligosaccharide Elicitors, and Ultraviolet-B Radiation at the Level of Mitogen-Activated Protein Kinases in Lycopersicon peruvianum Suspension-Cultured Cells
Plant Physiology, August 1, 2003; 132(4): 1728 - 1738.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
T. Soyano, R. Nishihama, K. Morikiyo, M. Ishikawa, and Y. Machida
NQK1/NtMEK1 is a MAPKK that acts in the NPK1 MAPKKK-mediated MAPK cascade and is required for plant cytokinesis
Genes & Dev., April 15, 2003; 17(8): 1055 - 1067.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2002 by the American Society of Plant Biologists