This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via ISI Web of Science (25) Citing Articles via Google Scholar Google Scholar Articles by Lawand, S. Articles by Carol, P. Search for Related Content PubMed PubMed Citation Articles by Lawand, S. Articles by Carol, P. Agricola Articles by Lawand, S. Articles by Carol, P.

Arabidopsis A BOUT DE SOUFFLE, Which Is Homologous with Mammalian Carnitine Acyl Carrier, Is Required for Postembryonic Growth in the Light

^a Laboratoire de Génétique Moleculaire des Plantes, Université Joseph Fourier, Unité Mixte de Recherche 5575, BP 53X, 38041 Grenoble, Cedex 09, France
^b Physiologie Cellulaire Végétale, Unité Mixte de Recherche 5019, Centre d'Etude Nucléaire de Grenoble, Rue des Martyrs, Grenoble, France
^c Department of Molecular Genetics, John Innes Centre, Norwich Research Park, Colney, Norwich, United Kingdom

² To whom correspondence should be addressed. E-mail pierre.carol{at}ujf-grenoble.fr; fax 33-476-51-43-36

The degradation of storage compounds just after germination is essential to plant development, providing energy and molecules necessary for the building of a photosynthetic apparatus and allowing autotrophic growth. We identified à bout de souffle (bou), a new Arabidopsis mutation. Mutant plants stopped developing after germination and degraded storage lipids, but they did not proceed to autotrophic growth. Neither leaves nor roots developed in the mutant. However, externally added sugar or germination in the dark could bypass this developmental block and allowed mutant plants to develop. The mutated gene was cloned using the transposon Dissociation as a molecular tag. The gene coding sequence showed similarity to those of the mitochondrial carnitine acyl carriers (CACs) or CAC-like proteins. In animals and yeast, these transmembrane proteins are involved in the transport of lipid-derived molecules across mitochondrial membranes for energy and carbon supply. The data presented here suggest that BOU identifies a novel mitochondrial pathway that is necessary to seedling development in the light. The BOU pathway would be an alternative to the well-known glyoxylate pathway.

This article has been cited by other articles:

				Y. Arai, M. Hayashi, and M. Nishimura Proteomic Identification and Characterization of a Novel Peroxisomal Adenine Nucleotide Transporter Supplying ATP for Fatty Acid {beta}-Oxidation in Soybean and Arabidopsis PLANT CELL, December 1, 2008; 20(12): 3227 - 3240. [Abstract] [Full Text] [PDF]

				C. Andre and C. Benning Arabidopsis Seedlings Deficient in a Plastidic Pyruvate Kinase Are Unable to Utilize Seed Storage Compounds for Germination and Establishment Plant Physiology, December 1, 2007; 145(4): 1670 - 1680. [Abstract] [Full Text] [PDF]

				N. Takata, J. Kasuga, D. Takezawa, K. Arakawa, and S. Fujikawa Gene expression associated with increased supercooling capability in xylem parenchyma cells of larch (Larix kaempferi) J. Exp. Bot., October 1, 2007; 58(13): 3731 - 3742. [Abstract] [Full Text] [PDF]

				K. A. Lucas, J. R. Filley, J. M. Erb, E. R. Graybill, and J. W. Hawes Peroxisomal Metabolism of Propionic Acid and Isobutyric Acid in Plants J. Biol. Chem., August 24, 2007; 282(34): 24980 - 24989. [Abstract] [Full Text] [PDF]

				A. Cernac, C. Andre, S. Hoffmann-Benning, and C. Benning WRI1 Is Required for Seed Germination and Seedling Establishment Plant Physiology, June 1, 2006; 141(2): 745 - 757. [Abstract] [Full Text] [PDF]

				N. A. Eckardt Peroxisomal Citrate Synthase Provides Exit Route from Fatty Acid Metabolism in Oilseeds PLANT CELL, July 1, 2005; 17(7): 1863 - 1865. [Full Text] [PDF]

				I. Pracharoenwattana, J. E. Cornah, and S. M. Smith Arabidopsis Peroxisomal Citrate Synthase Is Required for Fatty Acid Respiration and Seed Germination PLANT CELL, July 1, 2005; 17(7): 2037 - 2048. [Abstract] [Full Text] [PDF]

				J. E. Turner, K. Greville, E. C. Murphy, and M. A. Hooks Characterization of Arabidopsis Fluoroacetate-resistant Mutants Reveals the Principal Mechanism of Acetate Activation for Entry into the Glyoxylate Cycle J. Biol. Chem., January 28, 2005; 280(4): 2780 - 2787. [Abstract] [Full Text] [PDF]

				N. L. Taylor, J. L. Heazlewood, D. A. Day, and A. H. Millar Lipoic Acid-Dependent Oxidative Catabolism of {alpha}-Keto Acids in Mitochondria Provides Evidence for Branched-Chain Amino Acid Catabolism in Arabidopsis Plant Physiology, February 1, 2004; 134(2): 838 - 848. [Abstract] [Full Text] [PDF]

				J. L. Heazlewood, J. S. Tonti-Filippini, A. M. Gout, D. A. Day, J. Whelan, and A. H. Millar Experimental Analysis of the Arabidopsis Mitochondrial Proteome Highlights Signaling and Regulatory Components, Provides Assessment of Targeting Prediction Programs, and Indicates Plant-Specific Mitochondrial Proteins PLANT CELL, January 1, 2004; 16(1): 241 - 256. [Abstract] [Full Text] [PDF]