Plant Cell Illumina, Inc.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

First published online July 16, 2004; 10.1105/tpc.104.023093

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow PPT slides of all figures
Right arrow All Versions of this Article:
16/8/1959    most recent
tpc.104.023093v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (21)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shakirov, E. V.
Right arrow Articles by Shippen, D. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shakirov, E. V.
Right arrow Articles by Shippen, D. E.
Agricola
Right arrow Articles by Shakirov, E. V.
Right arrow Articles by Shippen, D. E.
The Plant Cell 16:1959-1967 (2004)
© 2004 American Society of Plant Biologists

Length Regulation and Dynamics of Individual Telomere Tracts in Wild-Type Arabidopsis

Eugene V. Shakirov and Dorothy E. Shippen1

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843-2128

1 To whom correspondence should be addressed. E-mail dshippen{at}tamu.edu; fax 979-845-9274.

Although length of the telomeric DNA tract varies widely across evolution, a species-specific set point is established and maintained by unknown mechanisms. To investigate how telomere length is controlled in Arabidopsis thaliana, we analyzed bulk telomere length in 14 wild-type accessions. We found that telomere tracts in Arabidopsis are fairly uniformly distributed throughout a size range of 2 to 9 kb. Unexpectedly, telomeres in plants of the Wassilewskija ecotype displayed a bimodal size distribution, with some individuals harboring telomeres of 2 to 5 kb and others telomeres of 4 to 9 kb. F1 and F2 progeny of a cross between long and short telomere parents had intermediate telomeres, implying that telomere length in Arabidopsis is not controlled by a single genetic factor. We provide evidence that although global telomere length is strictly regulated within an ecotype-specific range, telomere tracts on individual chromosome ends do not occupy a predetermined length territory. We also demonstrate that individual telomere tracts on homologous chromosomes are coordinately regulated throughout development and that telomerase acts preferentially on the shortest telomeres. We propose that an optimal size for telomere tracts is established and maintained for each Arabidopsis ecotype.




This article has been cited by other articles:


Home page
 Appl. Environ. Microbiol.Home page
G. Perez, J. Pangilinan, A. G. Pisabarro, and L. Ramirez
Telomere Organization in the Ligninolytic Basidiomycete Pleurotus ostreatus
Appl. Envir. Microbiol., March 1, 2009; 75(5): 1427 - 1436.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
X. Song, K. Leehy, R. T. Warrington, J. C. Lamb, Y. V. Surovtseva, and D. E. Shippen
STN1 protects chromosome ends in Arabidopsis thaliana
PNAS, December 16, 2008; 105(50): 19815 - 19820.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
K. Kannan, A. D. L. Nelson, and D. E. Shippen
Dyskerin Is a Component of the Arabidopsis Telomerase RNP Required for Telomere Maintenance
Mol. Cell. Biol., April 1, 2008; 28(7): 2332 - 2341.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
M. L. Heacock, R. A. Idol, J. D. Friesner, A. B. Britt, and D. E. Shippen
Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV
Nucleic Acids Res., October 8, 2007; 35(19): 6490 - 6500.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J.-P. Hong, M. Y. Byun, D.-H. Koo, K. An, J.-W. Bang, I. K. Chung, G. An, and W. T. Kim
Suppression of RICE TELOMERE BINDING PROTEIN1 Results in Severe and Gradual Developmental Defects Accompanied by Genome Instability in Rice
PLANT CELL, June 1, 2007; 19(6): 1770 - 1781.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
J. M. Watson and D. E. Shippen
Telomere Rapid Deletion Regulates Telomere Length in Arabidopsis thaliana
Mol. Cell. Biol., March 1, 2007; 27(5): 1706 - 1715.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
M. G. Hwang and M. H. Cho
Arabidopsis thaliana telomeric DNA-binding protein 1 is required for telomere length homeostasis and its Myb-extension domain stabilizes plant telomeric DNA binding
Nucleic Acids Res., February 28, 2007; 35(4): 1333 - 1342.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
H.-F. Kuo, K. M. Olsen, and E. J. Richards
Natural Variation in a Subtelomeric Region of Arabidopsis: Implications for the Genomic Dynamics of a Chromosome End
Genetics, May 1, 2006; 173(1): 401 - 417.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
E. V. Shakirov, Y. V. Surovtseva, N. Osbun, and D. E. Shippen
The Arabidopsis Pot1 and Pot2 Proteins Function in Telomere Length Homeostasis and Chromosome End Protection
Mol. Cell. Biol., September 1, 2005; 25(17): 7725 - 7733.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Ren, J. S. Johnston, D. E. Shippen, and T. D. McKnight
TELOMERASE ACTIVATOR1 Induces Telomerase Activity and Potentiates Responses to Auxin in Arabidopsis
PLANT CELL, November 1, 2004; 16(11): 2910 - 2922.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2004 by the American Society of Plant Biologists