Plant Cell Blood
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (103)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wei, N.
Right arrow Articles by Deng, X. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wei, N.
Right arrow Articles by Deng, X. W.
Agricola
Right arrow Articles by Wei, N.
Right arrow Articles by Deng, X. W.

THE PLANT CELL, Vol 4, Issue 12 1507-1518, Copyright © 1992 by American Society of Plant Biologists

RESEARCH ARTICLES

COP9: A New Genetic Locus Involved in Light-Regulated Development and Gene Expression in Arabidopsis

N. Wei and X. W. Deng
Department of Biology, Yale University, New Haven, Connecticut 06511

We report here the identification and characterization of a new Arabidopsis light-regulatory locus, COP9, mutation that leads to a constitutive photomorphogenic phenotype. Dark-grown cop9 seedlings exhibit many morphological characteristics of light-grown seedlings, including short hypocotyls and open and enlarged cotyledons with cell-type and chloroplast differentiation. Furthermore, the cop9 mutation leads to high-level expression of light-inducible genes in the absence of light, probably by altering the promoter activities of these genes. These properties imply that the mutation in the COP9 locus uncouples the light/dark signals from morphogenesis and light-regulated gene expression. In addition, light-grown cop9 mutants are severely dwarfed and are unable to reach maturation and flowering. This adult-lethal phenotype indicates that the COP9 locus also plays a critical role for normal development of the light-grown plant. Similar to cop1 mutants, but not det1, the cop9 mutants show (1) no effect on the phytochrome control of seed germination and (2) deficiency in the dark-adaptive change of expression of light-regulated genes. Our results suggest that the cop9 and cop1 mutations result in the same range of phenotypes and therefore COP9 and COP1 loci may encode closely related components in the same regulatory pathway.


This article has been cited by other articles:


Home page
 Mol. Biol. CellHome page
Z. Ullah, M. S. Buckley, D. N. Arnosti, and R. W. Henry
Retinoblastoma Protein Regulation by the COP9 Signalosome
Mol. Biol. Cell, April 1, 2007; 18(4): 1179 - 1186.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
G. Gusmaroli, S. Feng, and X. W. Deng
The Arabidopsis CSN5A and CSN5B Subunits Are Present in Distinct COP9 Signalosome Complexes, and Mutations in Their JAMM Domains Exhibit Differential Dominant Negative Effects on Development
PLANT CELL, November 1, 2004; 16(11): 2984 - 3001.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
L. Ma, H. Zhao, and X. W. Deng
Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development
Development, March 1, 2003; 130(5): 969 - 981.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
G. Serino, H. Su, Z. Peng, T. Tsuge, N. Wei, H. Gu, and X. W. Deng
Characterization of the Last Subunit of the Arabidopsis COP9 Signalosome: Implications for the Overall Structure and Origin of the Complex
PLANT CELL, March 1, 2003; 15(3): 719 - 731.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Sun, M. P. Wilson, and P. W. Majerus
Inositol 1,3,4-Trisphosphate 5/6-Kinase Associates with the COP9 Signalosome by Binding to CSN1
J. Biol. Chem., November 22, 2002; 277(48): 45759 - 45764.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
L. Ma, Y. Gao, L. Qu, Z. Chen, J. Li, H. Zhao, and X. W. Deng
Genomic Evidence for COP1 as a Repressor of Light-Regulated Gene Expression and Development in Arabidopsis
PLANT CELL, October 1, 2002; 14(10): 2383 - 2398.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
E. Oron, M. Mannervik, S. Rencus, O. Harari-Steinberg, S. Neuman-Silberberg, D. Segal, and D. A. Chamovitz
COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster
Development, January 10, 2002; 129(19): 4399 - 4409.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
Z. Peng, G. Serino, and X.-W. Deng
A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3
Development, November 1, 2001; 128(21): 4277 - 4288.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Z. Peng, G. Serino, and X.-W. Deng
Molecular Characterization of Subunit 6 of the COP9 Signalosome and Its Role in Multifaceted Developmental Processes in Arabidopsis
PLANT CELL, November 1, 2001; 13(11): 2393 - 2407.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
O. Harari-Steinberg, I. Ohad, and D. A. Chamovitz
Dissection of the Light Signal Transduction Pathways Regulating the Two Early Light-Induced Protein Genes in Arabidopsis
Plant Physiology, November 1, 2001; 127(3): 986 - 997.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
M. Seyedi, M. P. Timko, and C. Sundqvist
The Distribution of Protochlorophyllide and Chlorophyll within Seedlings of the lip1 Mutant of Pea
Plant Cell Physiol., September 1, 2001; 42(9): 931 - 941.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. E. Pepper, M.-s. Seong-Kim, S. M. Hebst, K. N. Ivey, S.-J. Kwak, and D. E. Broyles
shl, a New Set of Arabidopsis Mutants with Exaggerated Developmental Responses to Available Red, Far-Red, and Blue Light
Plant Physiology, September 1, 2001; 127(1): 295 - 304.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
D. Cao, Y. Lin, and C.-L. Cheng
Genetic Interactions between the Chlorate-Resistant Mutant cr 8 8 and the Photomorphogenic Mutants cop1 and hy5
PLANT CELL, February 1, 2000; 12(2): 199 - 210.
[Abstract] [Full Text]

Home page
 Plant CellHome page
G. Serino, T. Tsuge, S. Kwok, M. Matsui, N. Wei, and X.-W. Deng
Arabidopsis cop8 and fus4 Mutations Define the Same Gene That Encodes Subunit 4 of the COP9 Signalosome
PLANT CELL, October 1, 1999; 11(10): 1967 - 1980.
[Abstract] [Full Text]

Home page
 Plant CellHome page
S. F. Kwok, R. Solano, T. Tsuge, D. A. Chamovitz, J. R. Ecker, M. Matsui, and X.-W. Deng
Arabidopsis Homologs of a c-Jun Coactivator Are Present Both in Monomeric Form and in the COP9 Complex, and Their Abundance Is Differentially Affected by the Pleiotropic cop/det/fus Mutations
PLANT CELL, November 1, 1998; 10(11): 1779 - 1790.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Y. Y. Yamamoto, M. Matsui, L.-H. Ang, and X.-W. Deng
Role of a COP1 Interactive Protein in Mediating Light-Regulated Gene Expression in Arabidopsis
PLANT CELL, July 1, 1998; 10(7): 1083 - 1094.
[Abstract] [Full Text]

Home page
 Plant CellHome page
R. Azpiroz, Y. Wu, J. C. LoCascio, and K. A. Feldmann
An Arabidopsis Brassinosteroid-Dependent Mutant Is Blocked in Cell Elongation
PLANT CELL, February 1, 1998; 10(2): 219 - 230.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
U. Sperling, F. Franck, B. van Cleve, G. Frick, K. Apel, and G. A. Armstrong
Etioplast Differentiation in Arabidopsis: Both PORA and PORB Restore the Prolamellar Body and Photoactive Protochlorophyllide -F655 to the cop1 Photomorphogenic Mutant
PLANT CELL, February 1, 1998; 10(2): 283 - 296.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
P. Quail, M. Boylan, B. Parks, T. Short, Y Xu, and D Wagner
Phytochromes: photosensory perception and signal transduction
Science, May 5, 1995; 268(5211): 675 - 680.
[Abstract] [PDF]

Home page
 Genes Dev.Home page
H M Li, L Altschmied, and J Chory
Arabidopsis mutants define downstream branches in the phototransduction pathway.
Genes & Dev., February 1, 1994; 8(3): 339 - 349.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 1992 by the American Society of Plant Biologists