Plant Cell email content delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (105)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Martin, G. B.
Right arrow Articles by Tanksley, S. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Martin, G. B.
Right arrow Articles by Tanksley, S. D.
Agricola
Right arrow Articles by Martin, G. B.
Right arrow Articles by Tanksley, S. D.

THE PLANT CELL, Vol 6, Issue 11 1543-1552, Copyright © 1994 by American Society of Plant Biologists

RESEARCH ARTICLES

A Member of the Tomato Pto Gene Family Confers Sensitivity to Fenthion Resulting in Rapid Cell Death

G. B. Martin, A. Frary, T. Wu, S. Brommonschenkel, J. Chunwongse, E. D. Earle and S. D. Tanksley
Department of Agronomy, Purdue University, West Lafayette, Indiana 47907-1150

Leaves of tomato cultivars that contain the Pto bacterial resistance locus develop small necrotic lesions within 24 hr after exposure to fenthion, an organophosphorous insecticide. Recently, the Pto gene was isolated and shown to be a putative serine/threonine protein kinase. Pto is one member of a multigene family that is clustered within a 400-kb region on chromosome 5. Here, we report that another member of this gene family, termed Fen, is responsible for the sensitivity to fenthion. Fen was isolated by map-based cloning using closely linked DNA markers to identify a yeast artificial chromosome clone that spanned the Pto region. After transformation with the Fen gene under control of the cauliflower mosaic virus (CaMV) 35S promoter, tomato plants that are normally insensitive to fenthion rapidly developed extensive necrotic lesions upon exposure to fenthion. Two related insecticides, fensulfothion and fenitrothion, also elicited necrotic lesions specifically on Fen-transformed plants. Transgenic tomato plants harboring integrated copies of the Pto gene under control of the CaMV 35S promoter displayed sensitivity to fenthion but to a lesser extent than did wild-type fenthion-sensitive plants. The Fen protein shares 80% identity (87% similarity) with Pto but does not confer resistance to Pseudomonas syringae pv tomato. These results suggest that Pto and Fen participate in the same signal transduction pathway.


This article has been cited by other articles:


Home page
 J Exp BotHome page
D. Yee and D. R. Goring
The diversity of plant U-box E3 ubiquitin ligases: from upstream activators to downstream target substrates
J. Exp. Bot., March 1, 2009; 60(4): 1109 - 1121.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
L. E. Rose, C. H. Langley, A. J. Bernal, and R. W. Michelmore
Natural Variation in the Pto Pathogen Resistance Gene Within Species of Wild Tomato (Lycopersicon). I. Functional Analysis of Pto Alleles
Genetics, September 1, 2005; 171(1): 345 - 357.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. J. Bernal, Q. Pan, J. Pollack, L. Rose, A. Kozik, N. Willits, Y. Luo, M. Guittet, E. Kochetkova, and R. W. Michelmore
Functional Analysis of the Plant Disease Resistance Gene Pto Using DNA Shuffling
J. Biol. Chem., June 17, 2005; 280(24): 23073 - 23083.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
H. Qiao, F. Wang, L. Zhao, J. Zhou, Z. Lai, Y. Zhang, T. P. Robbins, and Y. Xue
The F-Box Protein AhSLF-S2 Controls the Pollen Function of S-RNase-Based Self-Incompatibility
PLANT CELL, September 1, 2004; 16(9): 2307 - 2322.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. von Roepenack-Lahaye, M.-A. Newman, S. Schornack, K. E. Hammond-Kosack, T. Lahaye, J. D. G. Jones, M. J. Daniels, and J. M. Dow
p-Coumaroylnoradrenaline, a Novel Plant Metabolite Implicated in Tomato Defense against Pathogens
J. Biol. Chem., October 31, 2003; 278(44): 43373 - 43383.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
D. A. Halterman, F. Wei, and R. P. Wise
Powdery Mildew-Induced Mla mRNAs Are Alternatively Spliced and Contain Multiple Upstream Open Reading Frames
Plant Physiology, February 1, 2003; 131(2): 558 - 567.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
W. Ramakrishna, J. Emberton, M. Ogden, P. SanMiguel, and J. L. Bennetzen
Structural Analysis of the Maize Rp1 Complex Reveals Numerous Sites and Unexpected Mechanisms of Local Rearrangement
PLANT CELL, December 1, 2002; 14(12): 3213 - 3223.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
B. K. Riely and G. B. Martin
Ancient origin of pathogen recognition specificity conferred by the tomato disease resistance gene Pto
PNAS, February 13, 2001; 98(4): 2059 - 2064.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
R. C. Grube, E. R. Radwanski, and M. Jahn
Comparative Genetics of Disease Resistance Within the Solanaceae
Genetics, June 1, 2000; 155(2): 873 - 887.
[Abstract] [Full Text]

Home page
 GeneticsHome page
Q. Pan, Y.-S. Liu, O. Budai-Hadrian, M. Sela, L. Carmel-Goren, D. Zamir, and R. Fluhr
Comparative Genetics of Nucleotide Binding Site-Leucine Rich Repeat Resistance Gene Homologues in the Genomes of Two Dicotyledons: Tomato and Arabidopsis
Genetics, May 1, 2000; 155(1): 309 - 322.
[Abstract] [Full Text]

Home page
 Plant CellHome page
Y.-Q. Gu, C. Yang, V. K. Thara, J. Zhou, and G. B. Martin
Pti4 Is Induced by Ethylene and Salicylic Acid, and Its Product Is Phosphorylated by the Pto Kinase
PLANT CELL, May 1, 2000; 12(5): 771 - 786.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
Q. Qi, R. V. S. Rajala, W. Anderson, C. Jiang, K. Rozwadowski, G. Selvaraj, R. Sharma, and R. Datla
Molecular Cloning, Genomic Organization, and Biochemical Characterization of Myristoyl-CoA:Protein N-Myristoyltransferase from Arabidopsis thaliana
J. Biol. Chem., March 24, 2000; 275(13): 9673 - 9683.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
C. BASBAUM, H. LEMJABBAR, M. LONGPHRE, D. LI, E. GENSCH, and N. MCNAMARA
Control of Mucin Transcription by Diverse Injury-induced Signaling Pathways
Am. J. Respir. Crit. Care Med., November 1, 1999; 160(5): S44 - 48.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
K. Suzuki, A. Yano, and H. Shinshi
Slow and Prolonged Activation of the p47 Protein Kinase during Hypersensitive Cell Death in a Culture of Tobacco Cells
Plant Physiology, April 1, 1999; 119(4): 1465 - 1472.
[Abstract] [Full Text]

Home page
 Plant Physiol.Home page
T. Hoffman, J. S. Schmidt, X. Zheng, and A. F. Bent
Isolation of Ethylene-Insensitive Soybean Mutants That Are Altered in Pathogen Susceptibility and Gene-for-Gene Disease Resistance
Plant Physiology, March 1, 1999; 119(3): 935 - 950.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. R. Grant, J. M. McDowell, A. G. Sharpe, M. de Torres Zabala, D. J. Lydiate, and J. L. Dangl
Independent deletions of a pathogen-resistance gene in Brassica and Arabidopsis
PNAS, December 22, 1998; 95(26): 15843 - 15848.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J. M. McDowell, M. Dhandaydham, T. A. Long, M. G. M. Aarts, S. Goff, E. B. Holub, and J. L. Dangl
Intragenic Recombination and Diversifying Selection Contribute to the Evolution of Downy Mildew Resistance at the RPP8 Locus of Arabidopsis
PLANT CELL, November 1, 1998; 10(11): 1861 - 1874.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. F. Warren, A. Henk, P. Mowery, E. Holub, and R. W. Innes
A Mutation within the Leucine-Rich Repeat Domain of the Arabidopsis Disease Resistance Gene RPS5 Partially Suppresses Multiple Bacterial and Downy Mildew Resistance Genes
PLANT CELL, September 1, 1998; 10(9): 1439 - 1452.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
X.-Q. Li, M. Jean, B. S. Landry, and G. G. Brown
Restorer genes for different forms of Brassica cytoplasmic male sterility map to a single nuclear locus that modifies transcripts of several mitochondrial genes
PNAS, August 18, 1998; 95(17): 10032 - 10037.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
G. E. D. Oldroyd and B. J. Staskawicz
Genetically engineered broad-spectrum disease resistance in tomato
PNAS, August 18, 1998; 95(17): 10300 - 10305.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
R. J. Wright, P. M. Thaxton, K. M. El-Zik, and A. H. Paterson
D-Subgenome Bias of Xcm Resistance Genes in Tetraploid Gossypium (Cotton) Suggests That Polyploid Formation Has Created Novel Avenues for Evolution
Genetics, August 1, 1998; 149(4): 1987 - 1996.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
B. Baker, P. Zambryski, B. Staskawicz, and S. P. Dinesh-Kumar
Signaling in Plant-Microbe Interactions
Science, May 2, 1997; 276(5313): 726 - 733.
[Abstract] [Full Text]

Home page
 ScienceHome page
X. Tang, R. D. Frederick, J. Zhou, D. A. Halterman, Y. Jia, and G. B. Martin
Initiation of Plant Disease Resistance by Physical Interaction of AvrPto and Pto Kinase
Science, December 20, 1996; 274(5295): 2060 - 2063.
[Abstract] [Full Text]

Home page
 ScienceHome page
S. R. Scofield, C. M. Tobias, J. P. Rathjen, J. H. Chang, D. T. Lavelle, R. W. Michelmore, and B. J. Staskawicz
Molecular Basis of Gene-for-Gene Specificity in Bacterial Speck Disease of Tomato
Science, December 20, 1996; 274(5295): 2063 - 2065.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. Chandra, G. B. Martin, and P. S. Low
The Pto kinase mediates a signaling pathway leading to the oxidative burst in tomato
PNAS, November 12, 1996; 93(23): 13393 - 13397.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Schulze-Muth, S. Irmler, G. Schroder, and J. Schroder
Novel Type of Receptor-like Protein Kinase from a Higher Plant (Catharanthus roseus). cDNA, GENE, INTRAMOLECULAR AUTOPHOSPHORYLATION, AND IDENTIFICATION OF A THREONINE IMPORTANT FOR AUTO- AND SUBSTRATE PHOSPHORYLATION
J. Biol. Chem., October 25, 1996; 271(43): 26684 - 26689.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 1994 by the American Society of Plant Biologists