|
THE PLANT CELL, Vol 6, Issue 5 629-643, Copyright © 1994 by American Society of Plant Biologists
Arabidopsis COP8, COP10, and COP11 Genes Are Involved in Repression of Photomorphogenic Development in Darkness
N. Wei, S. F. Kwok, A. G. von Arnim, A. Lee, T. W. McNellis, B. Piekos and X. W. Deng
Department of Biology, Osborn Memorial Laboratories, OML 301, Yale University, 165 Prospect Street, New Haven, Connecticut 06520-8104
Wild-type Arabidopsis seedlings are capable of following two developmental
programs: photomorphogenesis in the light and skotomorphogenesis in
darkness. Screening of Arabidopsis mutants for constitutive
photomorphogenic development in darkness resulted in the identification of
three new loci designated COP8, COP10, and COP11. Detailed examination of
the temporal morphological and cellular differentiation patterns of
wild-type and mutant seedlings revealed that in darkness, seedlings
homozygous for recessive mutations in COP8, COP10, and COP11 failed to
suppress the photomorphogenic developmental pathway and were unable to
initiate skotomorphogenesis. As a consequence, the mutant seedlings grown
in the dark had short hypocotyls and open and expanded cotyledons, with
characteristic photomorphogenic cellular differentiation patterns and
elevated levels of light-inducible gene expression. In addition, plastids
of dark-grown mutants were defective in etioplast differentiation. Similar
to cop1 and cop9, and in contrast to det1 (deetiolated), these new mutants
lacked dark-adaptive change of light-regulated gene expression and retained
normal phytochrome control of seed germination. Epistatic analyses with the
long hypocotyl hy1, hy2, hy3, hy4, and hy5 mutations suggested that these
three loci, similar to COP1 and COP9, act downstream of both phytochromes
and a blue light receptor, and probably HY5 as well. Further, cop8-1,
cop10-1, and cop11-1 mutants accumulated higher levels of COP1, a feature
similar to the cop9-1 mutant. These results suggested that COP8, COP10, and
COP11, together with COP1, COP9, and DET1, function to suppress the
photomorphogenic developmental program and to promote skotomorphogenesis in
darkness. The identical phenotypes resulting from mutations in COP8, COP9,
COP10, and COP11 imply that their encoded products function in close
proximity, possibly with some of them as a complex, in the same signal
transduction pathway.
This article has been cited by other articles:
|
|
|
|
 
L. Guo, J. Zhou, A. A. Elling, J.-B. F. Charron, and X. W. Deng
Histone Modifications and Expression of Light-Regulated Genes in Arabidopsis Are Cooperatively Influenced by Changing Light Conditions
Plant Physiology,
August 1, 2008;
147(4):
2070 - 2083.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Gusmaroli, P. Figueroa, G. Serino, and X. W. Deng
Role of the MPN Subunits in COP9 Signalosome Assembly and Activity, and Their Regulatory Interaction with Arabidopsis Cullin3-Based E3 Ligases
PLANT CELL,
February 1, 2007;
19(2):
564 - 581.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Chen, Y. Shen, X. Tang, L. Yu, J. Wang, L. Guo, Y. Zhang, H. Zhang, S. Feng, E. Strickland, et al.
Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex in Mediating Light Control of Development
PLANT CELL,
August 1, 2006;
18(8):
1991 - 2004.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Jiao, L. Ma, E. Strickland, and X. W. Deng
Conservation and Divergence of Light-Regulated Genome Expression Patterns during Seedling Development in Rice and Arabidopsis
PLANT CELL,
December 1, 2005;
17(12):
3239 - 3256.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Gusmaroli, S. Feng, and X. W. Deng
The Arabidopsis CSN5A and CSN5B Subunits Are Present in Distinct COP9 Signalosome Complexes, and Mutations in Their JAMM Domains Exhibit Differential Dominant Negative Effects on Development
PLANT CELL,
November 1, 2004;
16(11):
2984 - 3001.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Yanagawa, J. A. Sullivan, S. Komatsu, G. Gusmaroli, G. Suzuki, J. Yin, T. Ishibashi, Y. Saijo, V. Rubio, S. Kimura, et al.
Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes
Genes & Dev.,
September 1, 2004;
18(17):
2172 - 2181.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Alabadi, J. Gil, M. A. Blazquez, and J. L. Garcia-Martinez
Gibberellins Repress Photomorphogenesis in Darkness
Plant Physiology,
March 1, 2004;
134(3):
1050 - 1057.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Lagrange, M.-A. Hakimi, D. Pontier, F. Courtois, J. P. Alcaraz, D. Grunwald, E. Lam, and S. Lerbs-Mache
Transcription Factor IIB (TFIIB)-Related Protein (pBrp), a Plant-Specific Member of the TFIIB-Related Protein Family
Mol. Cell. Biol.,
May 1, 2003;
23(9):
3274 - 3286.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Ma, H. Zhao, and X. W. Deng
Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development
Development,
March 1, 2003;
130(5):
969 - 981.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Ma, Y. Gao, L. Qu, Z. Chen, J. Li, H. Zhao, and X. W. Deng
Genomic Evidence for COP1 as a Repressor of Light-Regulated Gene Expression and Development in Arabidopsis
PLANT CELL,
October 1, 2002;
14(10):
2383 - 2398.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Suzuki, Y. Yanagawa, S. F. Kwok, M. Matsui, and X.-W. Deng
Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis
Genes & Dev.,
March 1, 2002;
16(5):
554 - 559.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Oron, M. Mannervik, S. Rencus, O. Harari-Steinberg, S. Neuman-Silberberg, D. Segal, and D. A. Chamovitz
COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster
Development,
January 10, 2002;
129(19):
4399 - 4409.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Z. Peng, G. Serino, and X.-W. Deng
A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3
Development,
November 1, 2001;
128(21):
4277 - 4288.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Z. Peng, G. Serino, and X.-W. Deng
Molecular Characterization of Subunit 6 of the COP9 Signalosome and Its Role in Multifaceted Developmental Processes in Arabidopsis
PLANT CELL,
November 1, 2001;
13(11):
2393 - 2407.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Seyedi, M. P. Timko, and C. Sundqvist
The Distribution of Protochlorophyllide and Chlorophyll within Seedlings of the lip1 Mutant of Pea
Plant Cell Physiol.,
September 1, 2001;
42(9):
931 - 941.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. E. Pepper, M.-s. Seong-Kim, S. M. Hebst, K. N. Ivey, S.-J. Kwak, and D. E. Broyles
shl, a New Set of Arabidopsis Mutants with Exaggerated Developmental Responses to Available Red, Far-Red, and Blue Light
Plant Physiology,
September 1, 2001;
127(1):
295 - 304.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.-C. Cheng, K. Lertpiriyapong, S. Wang, and Z. R. Sung
The Role of the Arabidopsis ELD1 Gene in Cell Development and Photomorphogenesis in Darkness
Plant Physiology,
June 1, 2000;
123(2):
509 - 520.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
D. Cao, Y. Lin, and C.-L. Cheng
Genetic Interactions between the Chlorate-Resistant Mutant cr 8 8 and the Photomorphogenic Mutants cop1 and hy5
PLANT CELL,
February 1, 2000;
12(2):
199 - 210.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
G. Serino, T. Tsuge, S. Kwok, M. Matsui, N. Wei, and X.-W. Deng
Arabidopsis cop8 and fus4 Mutations Define the Same Gene That Encodes Subunit 4 of the COP9 Signalosome
PLANT CELL,
October 1, 1999;
11(10):
1967 - 1980.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
S. F. Kwok, R. Solano, T. Tsuge, D. A. Chamovitz, J. R. Ecker, M. Matsui, and X.-W. Deng
Arabidopsis Homologs of a c-Jun Coactivator Are Present Both in Monomeric Form and in the COP9 Complex, and Their Abundance Is Differentially Affected by the Pleiotropic cop/det/fus Mutations
PLANT CELL,
November 1, 1998;
10(11):
1779 - 1790.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Y. Yamamoto, M. Matsui, L.-H. Ang, and X.-W. Deng
Role of a COP1 Interactive Protein in Mediating Light-Regulated Gene Expression in Arabidopsis
PLANT CELL,
July 1, 1998;
10(7):
1083 - 1094.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
J. P. Vogel, P. Schuerman, K. Woeste, I. Brandstatter, and J. J. Kieber
Isolation and Characterization of Arabidopsis Mutants Defective in the Induction of Ethylene Biosynthesis by Cytokinin
Genetics,
May 1, 1998;
149(1):
417 - 427.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Chattopadhyay, L.-H. Ang, P. Puente, X.-W. Deng, and N. Wei
Arabidopsis bZIP Protein HY5 Directly Interacts with Light-Responsive Promoters in Mediating Light Control of Gene Expression
PLANT CELL,
May 1, 1998;
10(5):
673 - 684.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C.-Y. Hung, Y. Lin, M. Zhang, S. Pollock, M. David Marks, and J. Schiefelbein
A Common Position-Dependent Mechanism Controls Cell-Type Patterning and GLABRA2 Regulation in the Root and Hypocotyl Epidermis of Arabidopsis
Plant Physiology,
May 1, 1998;
117(1):
73 - 84.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
J. W. Reed, R. P. Elumalai, and J. Chory
Suppressors of an Arabidopsis thaliana phyB Mutation Identify Genes That Control Light Signaling and Hypocotyl Elongation
Genetics,
March 1, 1998;
148(3):
1295 - 1310.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Azpiroz, Y. Wu, J. C. LoCascio, and K. A. Feldmann
An Arabidopsis Brassinosteroid-Dependent Mutant Is Blocked in Cell Elongation
PLANT CELL,
February 1, 1998;
10(2):
219 - 230.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
U. Sperling, F. Franck, B. van Cleve, G. Frick, K. Apel, and G. A. Armstrong
Etioplast Differentiation in Arabidopsis: Both PORA and PORB Restore the Prolamellar Body and Photoactive Protochlorophyllide -F655 to the cop1 Photomorphogenic Mutant
PLANT CELL,
February 1, 1998;
10(2):
283 - 296.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Quail, M. Boylan, B. Parks, T. Short, Y Xu, and D Wagner
Phytochromes: photosensory perception and signal transduction
Science,
May 5, 1995;
268(5211):
675 - 680.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R. B. Goldberg, G. de Paiva, and R. Yadegari
Plant Embryogenesis: Zygote to Seed
Science,
October 28, 1994;
266(5185):
605 - 614.
[Abstract]
[PDF]
|
|
|
|
|
|
|
X. Wang, D. Kang, S. Feng, G. Serino, C. Schwechheimer, and N. Wei
CSN1 N-Terminal-dependent Activity Is Required for Arabidopsis Development But Not for Rub1/Nedd8 Deconjugation of Cullins: A Structure-Function Study of CSN1 Subunit of COP9 Signalosome
Mol. Biol. Cell,
February 1, 2002;
13(2):
646 - 655.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
