Plant Cell
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (66)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Moyano, E.
Right arrow Articles by Martin, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moyano, E.
Right arrow Articles by Martin, C.
Agricola
Right arrow Articles by Moyano, E.
Right arrow Articles by Martin, C.

THE PLANT CELL, Vol 8, Issue 9 1519-1532, Copyright © 1996 by American Society of Plant Biologists

RESEARCH ARTICLES

Apparent Redundancy in myb Gene Function Provides Gearing for the Control of Flavonoid Biosynthesis in Antirrhinum Flowers

E. Moyano, J. F. Martinez-Garcia and C. Martin
Department of Genetics, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, United Kingdom

Two Myb-related transcription factors, Myb305 and Myb340, are expressed specifically in flowers of Antirrhinum. The proteins are structurally very similar throughout their DNA binding domains, implying that they bind to common target motifs. This binding has been demonstrated experimentally. Myb305 has been shown to activate the gene encoding the first enzyme of phenylpropanoid metabolism, phenylalanine ammonia-lyase. We show that Myb340 can also activate transcription from the phenylalanine ammonia-lyase gene promoter and that both transcription factors can activate two other genes involved in flavonoid metabolism, thereby linking early and later steps in plant secondary metabolism. Myb340 is a stronger activator than Myb305, but relatively more Myb305 than Myb340 protein is able to bind to target promoters when both proteins are synthesized in yeast or Escherichia coli, probably as a result of inhibition of Myb340 binding by phosphorylation. This means that Myb305 can compete with Myb340 to reduce its effective transcriptional activation when both transcription factors are expressed in the same cell. This competitive interaction has been demonstrated in plant cells. Expression patterns determined by in situ hybridization showed that the two transcription factors are expressed within the same cells of the flower and imply that the detailed specializations in function of these two apparently redundant transcription factors may be used to provide gears that adjust the rate of induction of secondary metabolism to floral development.


This article has been cited by other articles:


Home page
 J Exp BotHome page
C. Bomal, F. Bedon, S. Caron, S. D. Mansfield, C. Levasseur, J. E. K. Cooke, S. Blais, L. Tremblay, M.-J. Morency, N. Pavy, et al.
Involvement of Pinus taeda MYB1 and MYB8 in phenylpropanoid metabolism and secondary cell wall biogenesis: a comparative in planta analysis
J. Exp. Bot., October 1, 2008; 59(14): 3925 - 3939.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
M. C. Palmieri, S. Sell, X. Huang, M. Scherf, T. Werner, J. Durner, and C. Lindermayr
Nitric oxide-responsive genes and promoters in Arabidopsis thaliana: a bioinformatics approach
J. Exp. Bot., February 13, 2008; (2008) erm345v1.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
F. W. Jaffe, A. Tattersall, and B. J. Glover
A truncated MYB transcription factor from Antirrhinum majus regulates epidermal cell outgrowth
J. Exp. Bot., April 1, 2007; 58(6): 1515 - 1524.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
C. Yang, Z. Xu, J. Song, K. Conner, G. Vizcay Barrena, and Z. A. Wilson
Arabidopsis MYB26/MALE STERILE35 Regulates Secondary Thickening in the Endothecium and Is Essential for Anther Dehiscence
PLANT CELL, February 1, 2007; 19(2): 534 - 548.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
R. A.E. Laitinen, J. Immanen, P. Auvinen, S. Rudd, E. Alatalo, L. Paulin, M. Ainasoja, M. Kotilainen, S. Koskela, T. H. Teeri, et al.
Analysis of the floral transcriptome uncovers new regulators of organ determination and gene families related to flower organ differentiation in Gerbera hybrida (Asteraceae)
Genome Res., April 1, 2005; 15(4): 475 - 486.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
P. Elomaa, A. Uimari, M. Mehto, V. A. Albert, R. A.E. Laitinen, and T. H. Teeri
Activation of Anthocyanin Biosynthesis in Gerbera hybrida (Asteraceae) Suggests Conserved Protein-Protein and Protein-Promoter Interactions between the Anciently Diverged Monocots and Eudicots
Plant Physiology, December 1, 2003; 133(4): 1831 - 1842.
[Abstract] [Full Text]

Home page
 Plant CellHome page
S. Penfield, R. C. Meissner, D. A. Shoue, N. C. Carpita, and M. W. Bevan
MYB61 Is Required for Mucilage Deposition and Extrusion in the Arabidopsis Seed Coat
PLANT CELL, December 1, 2001; 13(12): 2777 - 2791.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. Yang, J. P. Sweetman, S. Amirsadeghi, M. Barghchi, A. K. Huttly, W.-I. Chung, and D. Twell
Novel Anther-Specific myb Genes from Tobacco as Putative Regulators of Phenylalanine Ammonia-Lyase Expression
Plant Physiology, August 1, 2001; 126(4): 1738 - 1753.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. C. Meissner, H. Jin, E. Cominelli, M. Denekamp, A. Fuertes, R. Greco, H. D. Kranz, S. Penfield, K. Petroni, A. Urzainqui, et al.
Function Search in a Large Transcription Factor Gene Family in Arabidopsis: Assessing the Potential of Reverse Genetics to Identify Insertional Mutations in R2R3 MYB Genes
PLANT CELL, October 1, 1999; 11(10): 1827 - 1840.
[Abstract] [Full Text]

Home page
 GeneticsHome page
P. D. Rabinowicz, E. L. Braun, A. D. Wolfe, B. Bowen, and E. Grotewold
Maize R2R3 Myb Genes: Sequence Analysis Reveals Amplification in the Higher Plants
Genetics, September 1, 1999; 153(1): 427 - 444.
[Abstract] [Full Text]

Home page
 Plant CellHome page
F. Quattrocchio, J. Wing, K. van der Woude, E. Souer, N. de Vetten, J. Mol, and R. Koes
Molecular Analysis of the anthocyanin2 Gene of Petunia and Its Role in the Evolution of Flower Color
PLANT CELL, August 1, 1999; 11(8): 1433 - 1444.
[Abstract] [Full Text]

Home page
 Plant CellHome page
E. Grotewold, M. Chamberlin, M. Snook, B. Siame, L. Butler, J. Swenson, S. Maddock, G. St. Clair, and B. Bowen
Engineering Secondar y Metabolism in Maize Cells by Ectopic Expression of Transcription Factors
PLANT CELL, May 1, 1998; 10(5): 721 - 740.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
L. Tamagnone, A. Merida, A. Parr, S. Mackay, F. A. Culianez-Macia, K. Roberts, and C. Martin
The AmMYB308 and AmMYB330 Transcription Factors from Antirrhinum Regulate Phenylpropanoid and Lignin Biosynthesis in Transgenic Tobacco
PLANT CELL, February 1, 1998; 10(2): 135 - 154.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. T. Clegg, M. P. Cummings, and M. L. Durbin
The evolution of plant nuclear genes
PNAS, July 22, 1997; 94(15): 7791 - 7798.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
N de Vetten, F Quattrocchio, J Mol, and R Koes
The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals.
Genes & Dev., June 1, 1997; 11(11): 1422 - 1434.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 1996 by the American Society of Plant Biologists