Interactions between the Cell Cycle and Embryonic Patterning in Arabidopsis Uncovered by a Mutation in DNA Polymerase
Plant Cell Jenik et al.
17: 3362
Supplemental Data
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Supplemental Figure 1 -
Supplemental Figure 1. Alignment of DNA polymerase ε protein sequences. The protein sequences were aligned using the ClustalW method (MacGDE software package). The positions of til1 and til2mutations are indicated (red and green, respectively), as are the domains and subdomains (NT: N-terminal, Exo: 3¡¦-5¡¦ exonuclease, Pol: 5¡¦-3¡¦ polymerase, C: Central, P: PCNA interaction, Z: Zn-fingers). Domains are as described by D. Huang et al. (1999, Biochim. Biophys. Acta 1145:363-371) and H. Pospiech and J. Syväoja (2003, The Scientific World JOURNAL 3:87-104). GenBank accession numbers are: TILTED1: NP_172303; TILTED2: NP_180280; C. elegans (F33H2.5): NP_493616; D.melanogaster (dPOLE): NP_524462; H. sapiens (POLE1): AAP12650; M. musculus (POLE1): AAH63246; S. cerevisiae (Pol2): P21951;S. pombe (Cdc20): NP_596354, O. sativa:XP_465943.