Plant Cell Applied Biosystems SYBR(R) Cells-to-CT(TM) Kits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

First published online December 30, 2005; 10.1105/tpc.105.038943

The Plant Cell 18:412-421 (2006)
© 2006 American Society of Plant Biologists

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental Data
Right arrow All Versions of this Article:
18/2/412    most recent
tpc.105.038943v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (61)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chiou, T.-J.
Right arrow Articles by Su, C.-l.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chiou, T.-J.
Right arrow Articles by Su, C.-l.
Agricola
Right arrow Articles by Chiou, T.-J.
Right arrow Articles by Su, C.-l.

Regulation of Phosphate Homeostasis by MicroRNA in Arabidopsis[W]

Tzyy-Jen Chioua,1, Kyaw Aunga,b,2, Shu-I Lina,c,2, Chia-Chune Wua,2, Su-Fen Chianga and Chun-lin Sua,3

a Institute of BioAgricultural Sciences, Academia Sinica, Taipei 115, Taiwan, Republic of China
b Molecular and Biological Agricultural Sciences Program, Taiwan International Graduate Program, Academia Sinica, Taipei 115, Taiwan, Republic of China
c Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan, Republic of China

1 To whom correspondence should be addressed. E-mail tjchiou{at}gate.sinica.edu.tw; fax 886-2-26515600.

In this study, we reveal a mechanism by which plants regulate inorganic phosphate (Pi) homeostasis to adapt to environmental changes in Pi availability. This mechanism involves the suppression of a ubiquitin-conjugating E2 enzyme by a specific microRNA, miR399. Upon Pi starvation, the miR399 is upregulated and its target gene, a ubiquitin-conjugating E2 enzyme, is downregulated in Arabidopsis thaliana. Accumulation of the E2 transcript is suppressed in transgenic Arabidopsis overexpressing miR399. Transgenic plants accumulated five to six times the normal Pi level in shoots and displayed Pi toxicity symptoms that were phenocopied by a loss-of-function E2 mutant. Pi toxicity was caused by increased Pi uptake and by translocation of Pi from roots to shoots and retention of Pi in the shoots. Moreover, unlike wild-type plants, in which Pi in old leaves was readily retranslocated to other developing young tissues, remobilization of Pi in miR399-overexpressing plants was impaired. These results provide evidence that miRNA controls Pi homeostasis by regulating the expression of a component of the proteolysis machinery in plants.




This article has been cited by other articles:


Home page
 Plant Cell PhysiolHome page
S. Kim, J.-Y. Yang, J. Xu, I.-C. Jang, M. J. Prigge, and N.-H. Chua
Two Cap-Binding Proteins CBP20 and CBP80 are Involved in Processing Primary MicroRNAs
Plant Cell Physiol., November 1, 2008; 49(11): 1634 - 1644.
[Abstract] [Full Text] [PDF]

Home page
 ANN BOT (LOND)Home page
Z. Zhang, L. Wei, X. Zou, Y. Tao, Z. Liu, and Y. Zheng
Submergence-responsive MicroRNAs are Potentially Involved in the Regulation of Morphological and Metabolic Adaptations in Maize Root Cells
Ann. Bot., October 1, 2008; 102(4): 509 - 519.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
Q.-H. Zhu, A. Spriggs, L. Matthew, L. Fan, G. Kennedy, F. Gubler, and C. Helliwell
A diverse set of microRNAs and microRNA-like small RNAs in developing rice grains
Genome Res., September 1, 2008; 18(9): 1456 - 1465.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. K. Grennan
Phosphate Accumulation in Plants: Signaling
Plant Physiology, September 1, 2008; 148(1): 3 - 5.
[Full Text] [PDF]

Home page
 BioinformaticsHome page
Y. Xu, X. Zhou, and W. Zhang
MicroRNA prediction with a novel ranking algorithm based on random walks
Bioinformatics, July 1, 2008; 24(13): i50 - i58.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. E. Abdel-Ghany and M. Pilon
MicroRNA-mediated Systemic Down-regulation of Copper Protein Expression in Response to Low Copper Availability in Arabidopsis
J. Biol. Chem., June 6, 2008; 283(23): 15932 - 15945.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S.-I Lin, S.-F. Chiang, W.-Y. Lin, J.-W. Chen, C.-Y. Tseng, P.-C. Wu, and T.-J. Chiou
Regulatory Network of MicroRNA399 and PHO2 by Systemic Signaling
Plant Physiology, June 1, 2008; 147(2): 732 - 746.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
J. Zhou, F. Jiao, Z. Wu, Y. Li, X. Wang, X. He, W. Zhong, and P. Wu
OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants
Plant Physiology, April 1, 2008; 146(4): 1673 - 1686.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
J. P. Hammond and P. J. White
Sucrose transport in the phloem: integrating root responses to phosphorus starvation
J. Exp. Bot., January 1, 2008; 59(1): 93 - 109.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. K. Grennan
Arabidopsis MicroRNAs
Plant Physiology, January 1, 2008; 146(1): 3 - 4.
[Full Text] [PDF]

Home page
 Plant Physiol.Home page
B. N. Devaiah, V. K. Nagarajan, and K. G. Raghothama
Phosphate Homeostasis and Root Development in Arabidopsis Are Synchronized by the Zinc Finger Transcription Factor ZAT6
Plant Physiology, September 1, 2007; 145(1): 147 - 159.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. Yamasaki, S. E. Abdel-Ghany, C. M. Cohu, Y. Kobayashi, T. Shikanai, and M. Pilon
Regulation of Copper Homeostasis by Micro-RNA in Arabidopsis
J. Biol. Chem., June 1, 2007; 282(22): 16369 - 16378.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
C. A. Atkins and P. M. C. Smith
Translocation in Legumes: Assimilates, Nutrients, and Signaling Molecules
Plant Physiology, June 1, 2007; 144(2): 550 - 561.
[Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. Tesfaye, J. Liu, D. L. Allan, and C. P. Vance
Genomic and Genetic Control of Phosphate Stress in Legumes
Plant Physiology, June 1, 2007; 144(2): 594 - 603.
[Full Text] [PDF]

Home page
 Plant Physiol.Home page
G. Hernandez, M. Ramirez, O. Valdes-Lopez, M. Tesfaye, M. A. Graham, T. Czechowski, A. Schlereth, M. Wandrey, A. Erban, F. Cheung, et al.
Phosphorus Stress in Common Bean: Root Transcript and Metabolic Responses
Plant Physiology, June 1, 2007; 144(2): 752 - 767.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. Penterman, D. Zilberman, J. H. Huh, T. Ballinger, S. Henikoff, and R. L. Fischer
DNA demethylation in the Arabidopsis genome
PNAS, April 17, 2007; 104(16): 6752 - 6757.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
B. N. Devaiah, A. S. Karthikeyan, and K. G. Raghothama
WRKY75 Transcription Factor Is a Modulator of Phosphate Acquisition and Root Development in Arabidopsis
Plant Physiology, April 1, 2007; 143(4): 1789 - 1801.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Yehudai-Resheff, S. L. Zimmer, Y. Komine, and D. B. Stern
Integration of Chloroplast Nucleic Acid Metabolism into the Phosphate Deprivation Response in Chlamydomonas reinhardtii
PLANT CELL, March 1, 2007; 19(3): 1023 - 1038.
[Abstract] [Full Text] [PDF]

Home page
 RNAHome page
J. Bove, C. L.H. Hord, and M. A. Mullen
The blossoming of RNA biology: Novel insights from plant systems
RNA, December 1, 2006; 12(12): 2035 - 2046.
[Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
N. Arnaud, I. Murgia, J. Boucherez, J.-F. Briat, F. Cellier, and F. Gaymard
An Iron-induced Nitric Oxide Burst Precedes Ubiquitin-dependent Protein Degradation for Arabidopsis AtFer1 Ferritin Gene Expression
J. Biol. Chem., August 18, 2006; 281(33): 23579 - 23588.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. Sunkar, A. Kapoor, and J.-K. Zhu
Posttranscriptional Induction of Two Cu/Zn Superoxide Dismutase Genes in Arabidopsis Is Mediated by Downregulation of miR398 and Important for Oxidative Stress Tolerance
PLANT CELL, August 1, 2006; 18(8): 2051 - 2065.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
R. Bari, B. Datt Pant, M. Stitt, and W.-R. Scheible
PHO2, MicroRNA399, and PHR1 Define a Phosphate-Signaling Pathway in Plants
Plant Physiology, July 1, 2006; 141(3): 988 - 999.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
K. Aung, S.-I Lin, C.-C. Wu, Y.-T. Huang, C.-l. Su, and T.-J. Chiou
pho2, a Phosphate Overaccumulator, Is Caused by a Nonsense Mutation in a MicroRNA399 Target Gene
Plant Physiology, July 1, 2006; 141(3): 1000 - 1011.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ASPB Publications THE PLANT CELL PLANT PHYSIOLOGY
Copyright © 2006 by the American Society of Plant Biologists