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Plant Cell Advance Online Publication
Published on September 17, 2002; 10.1105/tpc.004564

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Received May 16, 2002
Accepted July 26, 2002

Different Regulatory Regions Are Required for the Vernalization-Induced Repression of FLOWERING LOCUS C and for the Epigenetic Maintenance of Repression

Candice C. Sheldon 1, Anna B. Conn 1, Elizabeth S. Dennis 1*, and W. James Peacock 1

1 Commonwealth Scientific and Industrial Research Organization, Plant Industry, Canberra, Australian Capital Territory 2601, Australia

* To whom correspondence should be addressed. E-mail: liz.dennis{at}csiro.au.

Vernalization, the promotion of flowering by a prolonged period of low temperature, results in repression of the floral repressor FLOWERING LOCUS C (FLC ) and in early flowering. This repression bears the hallmark of an epigenetic event: the low expression state is maintained over many cell division cycles, but expression is derepressed in progeny. We show that the two stages of the response of FLC to vernalization, the repression of FLC and the maintenance of the repression during growth at normal temperatures after vernalization, are mediated through different regions of the FLC gene. Both promoter and intragenic regions are required for the responses. We also identify a 75-bp region in the FLC promoter that, in addition to intragenic sequences, is required for expression in nonvernalized plants.




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