PT  - JOURNAL ARTICLE
AU  - Ritter, C.
AU  - Dangl, J. L.
TI  - Interference between Two Specific Pathogen Recognition Events Mediated by Distinct Plant Disease Resistance Genes.
AID  - 10.1105/tpc.8.2.251
DP  - 1996 Feb 01
TA  - The Plant Cell
PG  - 251--257
VI  - 8
IP  - 2
4099  - http://www.plantcell.org/content/8/2/251.short
4100  - http://www.plantcell.org/content/8/2/251.full
SO  - Plant Cell1996 Feb 01; 8
AB  - We demonstrate that the interaction of the avirulence gene avrRpt2 and the cognate resistance gene RPS2 interferes with the interaction of avrRpm1-RPM1 in Arabidopsis. Interference is mediated outside of the bacterial pathogen Pseudomonas syringae, presumably at the level of recognition of avr-dependent signals, yet does not require the wild-type RPS2 product. A numerical excess of P. syringae expressing avrRpm1 can overcome this interference in mixed inoculations. The interference of avrRpt2-RPS2 engagement with RPM1-dependent functions is mirrored by transcriptional activation of genes preferentially expressed during RPM1- or RPS2-mediated disease resistance reactions. This demonstration of interference between two plant disease resistance genes suggests that their products compete for a common element(s) in a signal transduction pathway leading to disease resistance.