Table 1.

Effect of the Fed-1 iLRE on Translational Efficiency

mRNATranslational Efficiencya (light units/min/mg Protein)Relative Rate of Translation
luc-A501,0831.0
Minimal Fed-1–luc–A5011,00010.2
Complete Fed-1–luc–A503,067b2.8
  • a Data calculated from the initial slopes of the curves shown in Figure 9.

  • b Value does not take into account the reduced mRNA stability or inhibition of luciferase enzyme activity associated with this construct.