CASTOR | castor-2 | |||
---|---|---|---|---|

Ion (X) | E_{rev} (mV) | P_{X}/P_{Cl−} | E_{rev} (mV) | P_{X}/P_{Cl−} |

K^{+} | 36 ± 2 (n = 40) | 6.0^{a} | 28 ± 2 (n = 48) | 3.7^{a} |

Na^{+} | 11 ± 1 (n = 8) | 1.6^{a} | 25 ± 3 (n = 13) | 3.2^{a} |

Ca^{2+} | −29 ± 2 (n = 13) | 0.5^{b} | −32 ± 2 (n = 19) | 0.6^{b} |

↵a Permeability ratios calculated from reversal potentials using equation E

_{rev}= RT/zF × ln(P_{K+}[K]_{o}/P_{Na+}[Na]_{i}).↵b Permeability ratios calculated from reversal potentials using equation E

_{rev}= RT/F × ln(√((4P_{Ca2+}[Ca]_{o}/P_{K+}[K]_{i})+1/4) − 1/2), where RT/F = 25.26 mV and Z = 1. The junction potential correction was as follows: NaCl (250 mM/20 mM, agar bridge, 2 M KCl), Vm = Vcmd + 2.3 mV; KCl (250 mM/20 mM, agar bridge, 2 M KCl), Vm = Vcmd + 1.2 mV; CaCl_{2}(125 mM/10 mM, agar bridge, 2 M KCl), Vm = Vcmd + 3.1 mV.