Table 3. Analysis of Currents Recorded in Inside-Out Configuration from Wild-Type and Mutant KAT1 Channels
0 min5 min7 min
V1/2SnV1/2SnV1/2Sn
KAT1 WTNDND3NDND3NDND3
KAT1 S676D−156.3 ± 1.5 mV13.2 ± 1.43−155.2 ± 1.7 mV17.3 ± 1.43−158.2 ± 1.7 mV19.7 ± 1.53
KAT1 WT + FC−157.5 ± 1.2 mV16.2 ± 1.43−159 ± 1.6 mV22 ± 1.43−156 ± 2 mV22.3 ± 1.83
  • The 0, 5, and 7 min indicate time after patch excision. V1/2, half activation potential; S, inverse slope coefficient; n, number of cells; WT, wild type.